Lexapro vs. Zoloft: What's the Difference?
Edited by Sawaira Riaz || By Sumera Saeed || Updated on October 27, 2023
Lexapro (escitalopram) and Zoloft (sertraline) are both SSRIs used to treat depression and anxiety, but they differ in molecular structure and side effects.
Key Differences
Lexapro, also known as escitalopram, and Zoloft, known as sertraline, are both selective serotonin reuptake inhibitors (SSRIs). They are commonly prescribed for depression and anxiety disorders.
Sumera Saeed
Oct 26, 2023
Lexapro is known for its efficacy in treating generalized anxiety disorder and major depressive disorder. Zoloft is also effective in these areas but has additional FDA approvals for conditions like PTSD and OCD.
Sumera Saeed
Oct 26, 2023
Both Lexapro and Zoloft work by increasing serotonin levels in the brain, but they differ slightly in their chemical structure, which can affect how individuals respond to each medication.
Sumera Saeed
Oct 26, 2023
Side effects of Lexapro can include nausea, sleepiness, and sexual dysfunction. Zoloft shares similar side effects, with the addition of possible weight gain and diarrhea in some cases.
Janet White
Oct 26, 2023
Lexapro is often considered to have a faster onset of action compared to Zoloft. However, individual responses can vary, and some may find Zoloft more effective for their symptoms.
Sumera Saeed
Oct 26, 2023
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Comparison Chart
Lexapro and Zoloft Definitions
Lexapro
Lexapro is used to manage anxiety disorders.
His anxiety was better managed after starting Lexapro.
Sumera Saeed
Oct 26, 2023
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Zoloft
Zoloft works by affecting serotonin levels.
Zoloft helped regulate her serotonin levels, improving her mood.
Sara Rehman
Oct 26, 2023
Lexapro
Lexapro is an SSRI, a type of antidepressant.
After trying different treatments, they found Lexapro, an SSRI, worked best.
Sawaira Riaz
Oct 26, 2023
Zoloft
Zoloft is also used to treat anxiety and PTSD.
Zoloft helped him cope with his PTSD symptoms.
Aimie Carlson
Oct 26, 2023
Lexapro
Lexapro is a medication used to treat depression.
The doctor prescribed Lexapro to help with her depressive symptoms.
Sumera Saeed
Oct 26, 2023
Zoloft
Zoloft belongs to the SSRI drug class.
His doctor recommended Zoloft, an SSRI, for his depression.
Sumera Saeed
Oct 26, 2023
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Lexapro
Lexapro requires a prescription.
You'll need a prescription to get Lexapro from the pharmacy.
Harlon Moss
Oct 26, 2023
Zoloft
Zoloft is a commonly prescribed antidepressant.
She was feeling better after taking Zoloft for a few weeks.
Sawaira Riaz
Oct 26, 2023
Lexapro
Lexapro can help in balancing brain chemicals.
Lexapro was effective in balancing her brain's serotonin levels.
Janet White
Oct 26, 2023
Zoloft
Zoloft requires medical supervision.
Regular check-ups are important when taking Zoloft.
Sara Rehman
Oct 26, 2023
Zoloft
A selective-serotonin reuptake inhibitor commonly prescribed as an antidepressant (trade name Zoloft)
Sumera Saeed
Aug 30, 2019
FAQs
What is Zoloft?
A medication that belongs to the SSRI class, used for depression, anxiety, PTSD, and OCD.
Sawaira Riaz
Oct 26, 2023
Does Zoloft lead to weight gain?
Some individuals may experience weight gain on Zoloft.
Aimie Carlson
Oct 26, 2023
Are there any common side effects of Lexapro?
Common side effects include nausea, sleepiness, and sexual dysfunction.
Janet White
Oct 26, 2023
How quickly does Lexapro work?
Lexapro may start to work in 1-2 weeks, with full effects in 4-6 weeks.
Sumera Saeed
Oct 26, 2023
Does Zoloft cause sleep problems?
It can, but it varies from person to person.
Sumera Saeed
Oct 26, 2023
What is Lexapro?
An antidepressant medication used to treat depression and anxiety.
Sumera Saeed
Oct 26, 2023
Can Lexapro be used for anxiety?
Yes, Lexapro is effective in treating anxiety disorders.
Harlon Moss
Oct 26, 2023
What makes Zoloft different from other SSRIs?
Its broader range of FDA approvals and side effect profile distinguishes it.
Janet White
Oct 26, 2023
Can Zoloft lead to dependency?
It's not addictive, but sudden cessation can lead to withdrawal symptoms.
Aimie Carlson
Oct 26, 2023
Can Lexapro cause weight gain?
Weight gain is not a common side effect of Lexapro.
Sumera Saeed
Oct 26, 2023
What's the onset time for Zoloft's effectiveness?
Zoloft may take several weeks to show its full effect.
Sumera Saeed
Oct 26, 2023
What are Zoloft's common side effects?
They include nausea, diarrhea, weight gain, and sexual dysfunction.
Sara Rehman
Oct 26, 2023
Is Zoloft safe during pregnancy?
Zoloft should only be used if the benefits outweigh the risks; consult a healthcare provider.
Sara Rehman
Oct 26, 2023
Can alcohol be consumed with Lexapro?
Alcohol should be avoided as it can increase side effects.
Aimie Carlson
Oct 26, 2023
Is it safe to drink alcohol while taking Zoloft?
Alcohol is not recommended as it can worsen side effects.
Harlon Moss
Oct 26, 2023
Is Lexapro addictive?
Lexapro is not considered addictive, but discontinuation should be gradual.
Aimie Carlson
Oct 26, 2023
Can Lexapro be taken during pregnancy?
It's important to consult a doctor as Lexapro can carry risks during pregnancy.
Sara Rehman
Oct 26, 2023
How is Lexapro different from other SSRIs?
Lexapro has a slightly different chemical structure and side effect profile.
Sumera Saeed
Oct 26, 2023
Can Lexapro cause insomnia?
Some people may experience insomnia as a side effect.
Janet White
Oct 26, 2023
About Author
Written by
Sumera SaeedSumera is an experienced content writer and editor with a niche in comparative analysis. At Diffeence Wiki, she crafts clear and unbiased comparisons to guide readers in making informed decisions. With a dedication to thorough research and quality, Sumera's work stands out in the digital realm. Off the clock, she enjoys reading and exploring diverse cultures.
Edited by
Sawaira RiazSawaira is a dedicated content editor at difference.wiki, where she meticulously refines articles to ensure clarity and accuracy. With a keen eye for detail, she upholds the site's commitment to delivering insightful and precise content.
