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Difference Between Hormone and Enzyme

Main Difference

The main difference between Hormone and Enzyme is that the Hormone is the substance that is produced by the organism and transported into tissue fluids causing stimulation of specific cells or tissues, whereas Enzyme is the substance that is produced by the living organism which acts as a catalyst to cause the biochemical reactions.

Hormone vs. Enzyme

A hormone is a regulatory substance; on the other hand, the enzyme is the catalytic substance. Hormone produces by the organisms and transports to target cells, causing the stimulation of the specific tissues and cells; on the flip side, the enzyme also produced by the living organism and acts as a catalyst to cause several biochemical reactions. The hormone has low molecular weight; on the opposite side, an enzyme has high molecular weight comparatively.

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The hormone is easily passable through the lipid cell membrane; on the other side of the coin, the enzyme is not passable through the lipid cell membrane. The hormone acts as signals which pass between the cells or organs; on the other side of the coin, the enzyme can only catalyze the chemical reactions by increasing metabolic rate. The regulated factors of the hormone are brain and external factors; on the other hand, the regulated factors of the enzyme are isoenzymes, covalent modification, protein turnover, proteolytic activation.

Each hormone has a great variety of functions such as reproduction, growth, and development; on the other hand, the enzyme has a unique and specific but specific function. The hormone acts far away from the site of production; on the flip side, the enzyme acts at the site of synthesis.

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The functions of hormone depend on negative and positive feedback; on the flip side, the functions of the enzyme on the presence and absence of substrate. The increase or decrease of the hormone causes some pathological changes in the body; the insufficiency of the hormone causes diseases.

Comparison Chart

HormoneEnzyme
It produced by the body and transported by the blood to the target cell and causes the regulation of different organs, tissues, and cellsIt produced by the body and acted near the site of synthesis
Regulatory Factors
Brain and external factorsAllosteric control, isoenzymes, covalent modification, and proteolytic activation
Molecular weight
Has low molecular weightHas high molecular weight
Effect of Age
Changes efficiency with the ageIt does not change its efficiency
Functions
It has diverse functionsIt has unique and specific functions
Effect of Temperature and PH
It has no effect of temperature and heatThe high temperature and pH affect it
Permeability
It is permeable through the cell membraneIt is impermeable through the cell membrane
Secretion
It secreted by both endocrine and exocrine glandsOnly exocrine glands secrete it
Examples
Oxytocin, cortisol, testosterone, and estrogenHydrolases, isomerase, and oxidases
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What is Hormone?

A hormone is a regulatory substance that is produced by the living organisms and transported by the blood far away from the site of secretion and acts on the different target cells such as cells, organs, and tissues. The hormone may secrete from both types of glands that are endocrine and exocrine. The main regulatory factors that regulate hormone production are mainly the brain and other external factors.

The functions of the hormone may have a variety of diversity, such as reproduction, growth, and development. The functions of the hormone depend on the positive and negative feedback systems. Its efficiency changes with the age of the human being. The molecular weight of the hormone is very low, and it is comparable with other body substances.

The functions of the hormone do not affect by the high temperature, heat, and pH of the body. It is the hormones that are involved in the formation of heat. Hormones are lipid-soluble substances so they can easily cross the cell membrane. The examples of hormones in animals are estrogen, testosterone, oxytocin, cortisol, and in plants are abscisic acid, cytokines, and gibberellins.

What is an Enzyme?

The enzyme is the catalytic substance that is produced by living organisms. It acts where they are secreted or far away from the site of synthesis. It causes catalysis of many biochemical reactions. Only the exocrine gland system secretes enzymes. The main regulatory factors of enzyme production are isoenzymes, covalent modification, proteolytic activation, and protein turnover.

The functions of enzymes are unique and specific causes an increase in the speed of the specific biochemical reactions by a specific enzyme. Its function mainly depends on the substrate amount in cells. Its efficiency does not change with the age of the human body. The molecular weight of the enzyme is very high as compared to the other body substances.

The functions of enzymes effect by the high temperature, heat, and pH. Enzymes cause the breakdown of large molecules into smaller molecules or the union of small molecules into large molecules. Enzymes are lipid insoluble, so they cannot cross the lipid cell membrane. That’s why each enzyme is produced within the cell cytoplasm and nucleus and utilized within the cell. Examples of enzymes are hydrolases, oxidases, isomerases, peroxidases, and catalases, etc.

Key Differences

  1. The hormone produced by the body and acts on different tissues and cells as a regulatory substance; on the other hand, the enzyme is produced by the body and acts on different substrates.
  2. The function of the hormone depends on negative and positive feedback systems, whereas the function of the enzyme depends on the amount of substrate in the cell.
  3. The increase or decrease of hormone levels causes pathological diseases; on the flip side, the insufficiency of enzyme mainly causes diseases.
  4. The efficiency of hormone changes with age, whereas the efficiency of the enzyme remains the same and does not change with age.
  5. Hormone produces by both the endocrine and exocrine gland, on the other hand, the enzyme produces by exocrine glands.
  6. The hormone has low molecular weight; on the flip side, the enzyme has high molecular weight comparatively.
  7. The hormone is the regulatory substance, whereas the enzyme is the catalytic substance.
  8. A hormone is not affected by the high temperature and pH; on the opposite side, the enzyme is affected by high temperature and pH.
  9. The hormone has diverse functions; on the other hand, the enzyme has a unique and specific function.
  10. The regulating factors of the hormone are brain and external factors; on the flip side, the regulating factors of the enzyme are isoenzymes, covalent modification, protein turnover, and allosteric control.

Conclusion

The above discussion concludes that Hormone is produced by both endocrine and exocrine glands, whereas the exocrine glands produce the Enzyme.

Janet White

Janet White is a writer and blogger for Difference Wiki since 2015. She has a master's degree in science and medical journalism from Boston University. Apart from work, she enjoys exercising, reading, and spending time with her friends and family. Connect with her on Twitter @Janet__White