Genomics vs. Proteomics
Key Differences
Comparison Chart
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Phenomena
Classification
Important Areas
Study Of
Nature of Study Material
Importance
Genomics and Proteomics Definitions
Genomics
Proteomics
Genomics
Proteomics
Genomics
Proteomics
Genomics vs. Proteomics
Genomics comprises analysis of genomes, sequencing, and mapping, while proteomics contains the function and 3D structures of proteins, and various protein-protein relations. Genomics is classified into two types functional genomics and structural genomics, whereas proteomics is classified into three types that are functional, structural, and expression proteomics.
The important areas of genomics are the genome sequencing projects, which include the Human Genome Project; on the other hand, several important areas of proteomics are the proteome database developments, which are software development for computer-aided drug design and SWISS-2DPAGE. Genomics is the study of entire genes in organisms; on the contrary, proteomics is generally the study of entire proteins in various cells.
In genomics, the genome is usually constant, and all cells have the same set of genes in all organisms; conversely, in proteomics, the proteome usually varies and dynamic and all the set of proteins form in various tissues of organisms conferring to the gene expression. In genomics, the study of genes plays an important role in understanding the function, location, structure, and regulation of the genes in organisms; on the flip side, in proteomics, the study of proteins helps in understanding the structure and functions of proteins in cells.
What is Genomics?
The term genomics is defined as the whole study of genes in the entire genome of the cell in all the organisms. The genome which is present in the cells of organisms contains the whole set of genetic material, which is chiefly made of DNA. A high level of techniques is used to analysis of genomes, sequencing, and mapping of genomes.
Various gene sequencing strategies are used in genomics, which is sequencing, construction of expressed sequence tags (ESTs), whole-genome shotgun sequencing, directed gene, identification of single nucleotide polymorphisms (SNPs), and the analysis or explanation of sequenced data using different software and database. Genomics is classified into two types functional genomics and structural genomics.
Types
- Functional Genomics: Vital role and various functions of the genes in cells in modifying metabolic actions are studied under functional genomics.
- Structural Genomics: The relative positions and structure of the genes are studied under structural genomics.
What is Proteomics?
The term proteomics is defined as the entire study of proteins, which are generally produced by the cells in all organisms. The proteomes are generally the complete set of proteins that are normally produced by the various cells of all organisms. Proteomics contains the function and 3D structures of proteins, and various protein-protein relations.
Various techniques are involved in the proteomics process, for instance, digestion of proteins with the use of trypsin into minimum sized fragments, extraction and electrophoretic separation of proteins, identification of proteins using the information in the protein database, determination of the amino acid sequence by mass spectrometry. Proteomics is classified into three types that are functional, structural, and expression proteomics.
