Cleavage vs. Mitosis: What's the Difference?
Edited by Huma Saeed || By Sumera Saeed || Updated on October 29, 2023
Cleavage is rapid cell division without growth in early embryos; mitosis is the process where a single cell divides to produce two identical daughter cells.
Key Differences
Cleavage and mitosis are fundamental processes in cell biology. While cleavage specifically refers to the rapid cell divisions seen in early embryos without significant growth between divisions, mitosis is a broader term that describes the division of a single nucleus into two genetically identical daughter nuclei.
Sumera Saeed
Oct 29, 2023
During cleavage, the early embryo divides successively to produce many cells, but the overall size of the embryo doesn't increase substantially. In contrast, mitosis in somatic cells is typically followed by cytokinesis and is associated with growth and repair, leading to an increase in the overall size or number of cells in an organism.
Sumera Saeed
Oct 29, 2023
Cleavage typically lacks the G1 and G2 phases seen in the cell cycle of somatic cells, making the process faster. On the other hand, mitosis is just one part of the cell cycle, which also includes G1, S, and G2 phases, allowing time for the cell to grow and DNA to replicate.
Sumera Saeed
Oct 29, 2023
In cleavage, the resulting cells (or blastomeres) become progressively smaller with each division. In mitosis, each division results in daughter cells that, under normal circumstances, are identical in size and genetic content to the original cell.
Sumera Saeed
Oct 29, 2023
Both cleavage and mitosis are essential for life. While cleavage ensures the rapid multiplication of cells during the early developmental stages of an embryo, mitosis ensures that organisms can grow, repair damaged tissues, and reproduce .
Aimie Carlson
Oct 29, 2023
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Comparison Chart
Definition
Rapid cell division in embryos
Division producing two identical daughter cells
Sumera Saeed
Oct 29, 2023
Phases in the cell cycle
Lacks G1 and G2 phases
Includes G1, S, G2, and M phases
Sumera Saeed
Oct 29, 2023
Resulting cell size
Cells get progressively smaller
Daughter cells usually same size as parent
Sumera Saeed
Oct 29, 2023
Cleavage and Mitosis Definitions
Cleavage
Cleavage divisions are essential for early embryonic development.
Abnormalities during cleavage can affect the proper development of the embryo.
Aimie Carlson
Oct 29, 2023
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Mitosis
Mitosis occurs in somatic cells and is essential for growth and repair.
When you get a cut, the surrounding skin cells replicate via mitosis to heal the wound.
Sumera Saeed
Oct 29, 2023
Cleavage
In cleavage, the resulting cells, or blastomeres, decrease in size with each division.
As cleavage progresses, the blastomeres in the sea urchin embryo become notably smaller.
Sumera Saeed
Oct 29, 2023
Mitosis
Mitosis is the division of a single nucleus into two genetically identical daughter nuclei.
Human skin cells undergo mitosis to replace old or damaged cells.
Huma Saeed
Oct 29, 2023
Cleavage
Cleavage lacks typical cell growth phases, making the process swift.
The rapidity of cleavage can be attributed to the absence of certain cell cycle phases.
Sara Rehman
Oct 29, 2023
Mitosis
Mitosis is a crucial part of the cell cycle, ensuring genetic continuity.
Mitosis ensures that each daughter cell inherits the same genetic information.
Sumera Saeed
Oct 29, 2023
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Cleavage
Cleavage results in an increase in cell number without a significant increase in volume.
Despite multiple rounds of cleavage, the zebrafish embryo remains roughly the same size.
Sumera Saeed
Oct 29, 2023
Mitosis
Mitosis is a precise process ensuring genetic material is evenly distributed to daughter cells.
Errors in mitosis can lead to cells with an abnormal number of chromosomes.
Sara Rehman
Oct 29, 2023
Cleavage
Cleavage refers to the rapid and successive cell divisions in early embryos.
During the early stages of development, the frog embryo undergoes cleavage to form a ball of cells.
Huma Saeed
Oct 29, 2023
Mitosis
Mitosis leads to the production of two identical daughter cells from a single parent cell.
After mitosis, the two resulting cells are genetically identical to the original cell.
Sumera Saeed
Oct 29, 2023
FAQs
How does mitosis differ from meiosis?
Mitosis produces two identical daughter cells, while meiosis results in four genetically diverse sex cells.
Huma Saeed
Oct 29, 2023
Is mitosis only observed in animals?
No, mitosis occurs in both plants and animals.
Harlon Moss
Oct 29, 2023
Why is cleavage essential in early development?
Cleavage rapidly increases cell numbers, setting the stage for further embryonic development.
Sumera Saeed
Oct 29, 2023
Do cells grow in size during cleavage?
No, in cleavage, the overall embryo size remains roughly constant as cells divide.
Sumera Saeed
Oct 29, 2023
At what stage does mitosis occur in the cell cycle?
Mitosis is a phase in the cell cycle, following G2 and preceding cytokinesis.
Janet White
Oct 29, 2023
How many divisions occur during cleavage?
Cleavage involves multiple rapid divisions, with the number varying among organisms.
Janet White
Oct 29, 2023
Where in the body can we observe mitosis?
Mitosis can be observed in all actively growing and repairing tissues.
Sumera Saeed
Oct 29, 2023
What is cleavage?
Cleavage is rapid cell division without growth seen in early embryos.
Sumera Saeed
Oct 29, 2023
Why don't cells grow between cleavage divisions?
Cleavage lacks the G1 and G2 growth phases, so cells divide rapidly without significant growth.
Sumera Saeed
Oct 29, 2023
Does cleavage only happen in the early stages of development?
Cleavage is predominantly an early developmental event, setting the stage for further differentiation.
Sara Rehman
Oct 29, 2023
What are blastomeres in cleavage?
Blastomeres are the cells resulting from cleavage divisions in an embryo.
Janet White
Oct 29, 2023
Does mitosis always result in cell division?
Mitosis leads to the division of the nucleus, usually followed by cytokinesis, which divides the cell.
Sumera Saeed
Oct 29, 2023
How do blastomeres relate to cleavage?
Blastomeres are the product of cleavage divisions in early embryos.
Sara Rehman
Oct 29, 2023
Are mitotic cells always genetically identical?
Ideally, yes, but errors can lead to genetic variations or mutations.
Janet White
Oct 29, 2023
What ensures identical daughter cells in mitosis?
Proper segregation of chromosomes ensures each daughter cell gets identical genetic information.
Aimie Carlson
Oct 29, 2023
Can cleavage be seen in all animals?
While cleavage is common in many animals, the specifics can vary based on the species and egg type.
Sumera Saeed
Oct 29, 2023
Can mitosis repair damaged tissues?
Yes, mitosis allows cells to replicate and replace damaged or worn-out cells.
Sumera Saeed
Oct 29, 2023
Is cleavage unique to vertebrates?
No, cleavage is observed in various organisms, not just vertebrates.
Harlon Moss
Oct 29, 2023
What ensures the accuracy of mitosis?
Checkpoints and molecular machinery work together to ensure the fidelity of mitosis.
Janet White
Oct 29, 2023
Is DNA replication part of mitosis?
No, DNA replication occurs in the S phase, which precedes mitosis.
Janet White
Oct 29, 2023
About Author
Written by
Sumera SaeedSumera is an experienced content writer and editor with a niche in comparative analysis. At Diffeence Wiki, she crafts clear and unbiased comparisons to guide readers in making informed decisions. With a dedication to thorough research and quality, Sumera's work stands out in the digital realm. Off the clock, she enjoys reading and exploring diverse cultures.
Edited by
Huma SaeedHuma is a renowned researcher acclaimed for her innovative work in Difference Wiki. Her dedication has led to key breakthroughs, establishing her prominence in academia. Her contributions continually inspire and guide her field.
