Difference Wiki

YAC Vector vs. BAC Vector: What's the Difference?

Edited by Sawaira Riaz || By Sumera Saeed || Updated on October 27, 2023
YAC vectors (yeast artificial chromosomes) are used to clone large DNA fragments, while BAC vectors (bacterial artificial chromosomes) are for cloning moderately large DNA sequences.

Key Differences

YAC vectors are constructed using yeast DNA elements and can accommodate very large DNA inserts, up to several million base pairs. BAC vectors, derived from bacterial F-plasmid, typically hold DNA fragments up to 300,000 base pairs.
Sumera Saeed
Oct 27, 2023
In YAC vectors, cloning large fragments can lead to stability issues and chimerism. BAC vectors are more stable and have lower chances of rearrangement, making them more reliable for certain applications.
Sumera Saeed
Oct 27, 2023
YAC vectors are useful for cloning large genomic libraries and studying large genes or gene clusters. BAC vectors are commonly used in genome sequencing projects due to their stability and ease of manipulation.
Sumera Saeed
Oct 27, 2023
The maintenance and replication of YAC vectors depend on yeast cellular machinery. In contrast, BAC vectors replicate within bacterial cells, utilizing bacterial replication systems.
Aimie Carlson
Oct 27, 2023
YAC vectors require specialized yeast handling techniques for manipulation. BAC vectors, on the other hand, are manipulated using standard bacterial molecular biology techniques, making them more accessible.
Sara Rehman
Oct 27, 2023
ADVERTISEMENT

Comparison Chart

Origin

Yeast Artificial Chromosome
Bacterial Artificial Chromosome
Sumera Saeed
Oct 27, 2023

DNA Capacity

Up to several million base pairs
Up to 300,000 base pairs
Sumera Saeed
Oct 27, 2023

Stability

Less stable, prone to chimerism and rearrangements
More stable, fewer rearrangements
Sumera Saeed
Oct 27, 2023

Common Uses

Large genomic libraries, studying large genes
Genome sequencing, precise genetic engineering
Sara Rehman
Oct 27, 2023

Host Organism

Yeast
Bacteria
Sara Rehman
Oct 27, 2023
ADVERTISEMENT

Manipulation

Requires specialized yeast handling techniques
Standard bacterial molecular biology techniques
Sumera Saeed
Oct 27, 2023

Cloning Efficiency

Lower efficiency due to size and complexity
Higher efficiency
Sumera Saeed
Oct 27, 2023

Cost and Accessibility

Generally more complex and costly
More cost-effective and accessible
Janet White
Oct 27, 2023

Applications

Useful for studying complex genetic arrangements
Ideal for precise genetic studies and modifications
Janet White
Oct 27, 2023

YAC Vector and BAC Vector Definitions

YAC Vector

A vector capable of carrying large DNA inserts.
The YAC vector facilitated the cloning of the entire genomic region.
Sumera Saeed
Oct 27, 2023

BAC Vector

A tool for precise genetic engineering.
Geneticists used a BAC vector for targeted gene modifications.
Sumera Saeed
Oct 27, 2023

YAC Vector

A vector used in advanced genetic research.
The YAC vector played a crucial role in their genetic study.
Sara Rehman
Oct 27, 2023

BAC Vector

A system for cloning DNA fragments up to 300,000 base pairs.
The BAC vector successfully cloned the 200,000 base pair sequence.
Aimie Carlson
Oct 27, 2023

YAC Vector

A tool for studying eukaryotic gene function.
Researchers utilized a YAC vector to investigate the gene of interest.
Sumera Saeed
Oct 27, 2023

BAC Vector

A vector preferred for its stability and ease of manipulation.
Researchers chose the BAC vector due to its reliable performance.
Sumera Saeed
Oct 27, 2023

YAC Vector

A system used in constructing genomic libraries.
They constructed a genomic library using a YAC vector.
Sumera Saeed
Oct 27, 2023

BAC Vector

A cloning vector derived from bacterial plasmids.
The BAC vector was ideal for cloning the moderate-sized DNA fragment.
Sawaira Riaz
Oct 27, 2023

YAC Vector

A cloning vector derived from yeast chromosomes.
The YAC vector was used to clone the large DNA segment.
Sawaira Riaz
Oct 27, 2023

BAC Vector

A vector used in genome sequencing projects.
The human genome project extensively utilized BAC vectors.
Sumera Saeed
Oct 27, 2023

FAQs

What is a YAC vector?

A cloning vector derived from yeast chromosomes for large DNA fragments.
Sumera Saeed
Oct 27, 2023

Are YAC vectors stable?

YAC vectors are less stable and prone to rearrangements.
Harlon Moss
Oct 27, 2023

What is a BAC vector?

A cloning vector from bacterial plasmids for moderately large DNA fragments.
Sawaira Riaz
Oct 27, 2023

What are YAC vectors commonly used for?

They're used for cloning large genomic libraries and studying large genes.
Harlon Moss
Oct 27, 2023

What are BAC vectors commonly used for?

They're used in genome sequencing and precise genetic engineering.
Sumera Saeed
Oct 27, 2023

What organism hosts YAC vectors?

YAC vectors are maintained and replicated in yeast cells.
Sumera Saeed
Oct 27, 2023

Can BAC vectors be used in genome projects?

Yes, BAC vectors are extensively used in genome sequencing projects.
Sumera Saeed
Oct 27, 2023

What size DNA can BAC vectors accommodate?

BAC vectors typically hold DNA fragments up to 300,000 base pairs.
Sara Rehman
Oct 27, 2023

What is the cloning efficiency of BAC vectors?

BAC vectors have higher efficiency.
Sara Rehman
Oct 27, 2023

Do YAC vectors have applications beyond cloning?

They are also used for studying complex genetic arrangements.
Aimie Carlson
Oct 27, 2023

What organism hosts BAC vectors?

BAC vectors are maintained and replicated in bacterial cells.
Sumera Saeed
Oct 27, 2023

Are BAC vectors cost-effective?

BAC vectors are more cost-effective and accessible.
Janet White
Oct 27, 2023

Do BAC vectors have applications beyond cloning?

They are ideal for precise genetic studies and modifications.
Harlon Moss
Oct 27, 2023

What is the cloning efficiency of YAC vectors?

YAC vectors have lower efficiency due to their size and complexity.
Sumera Saeed
Oct 27, 2023

Are BAC vectors stable?

BAC vectors are more stable with fewer rearrangements.
Aimie Carlson
Oct 27, 2023

How are BAC vectors manipulated?

They are manipulated using standard bacterial molecular biology techniques.
Sumera Saeed
Oct 27, 2023

Are YAC vectors cost-effective?

YAC vectors are generally more complex and costly.
Aimie Carlson
Oct 27, 2023

What size DNA can YAC vectors accommodate?

YAC vectors can accommodate DNA fragments up to several million base pairs.
Sumera Saeed
Oct 27, 2023

Can YAC vectors be used in genetic research?

Yes, they are used in advanced genetic research.
Sumera Saeed
Oct 27, 2023

How are YAC vectors manipulated?

They require specialized yeast handling techniques.
Sumera Saeed
Oct 27, 2023
About Author
Written by
Sumera Saeed
Sumera is an experienced content writer and editor with a niche in comparative analysis. At Diffeence Wiki, she crafts clear and unbiased comparisons to guide readers in making informed decisions. With a dedication to thorough research and quality, Sumera's work stands out in the digital realm. Off the clock, she enjoys reading and exploring diverse cultures.
Edited by
Sawaira Riaz
Sawaira is a dedicated content editor at difference.wiki, where she meticulously refines articles to ensure clarity and accuracy. With a keen eye for detail, she upholds the site's commitment to delivering insightful and precise content.

Trending Comparisons

Popular Comparisons

New Comparisons