Difference Wiki

Nucleoside vs. Nucleotide

Nucleoside and Nucleotide both are nitrogenous bases linked with a five carbon sugar, whereas Nucleotide differs from nucleoside as it is further linked up with one or more phosphate groups. Nucleotide = Carbon sugar + Nitrogenous Base + Phosphate. Nucleoside = Carbon sugar + Nitrogenous Base

Key Differences

Nucleoside consist of carbon sugar and nitrogenous base only.
Nucleoside analogs are used in medicines as antiviral and anticancer agents.
Nucleotide work as a catalyst as well and stores information while as part of DNA and RNA.
Nucleotides are the building blocks and simplest functional unit of RNA and DNA.
A nucleotide consists of carbon sugar, nitrogenous base, and phosphate group as well.

Comparison Chart

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Nucleosides are organic molecules that contain a carbon sugar attached to a nitrogenous base.
Nucleotides are the organic molecules that contain a carbon sugar attached to a nitrogenous base and a phosphate group as well.
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Examples

Common sort of nucleoside includes adenosine, uridine, inosine, thymidine, cytidine, guanosine, etc.
Common examples include adenosine triphosphate, adenosine monophosphate, uridine monophosphate, etc.

Uses

A nucleoside is used to develop nucleotides that are building blocks of DNA and RNA. They are also used as the antiviral and anticancer agent.
Nucleotides are the simplest functional unit of DNA and RNA. They are the building blocks of RNA and DNA. The store's data and also work as a catalyst.

Building Block of RNA/DNA

No
Yes

Nucleoside and Nucleotide Definitions

Nucleoside

Any of various compounds, such as adenosine or guanosine, that consist of a sugar, usually ribose or deoxyribose, linked to a purine or pyrimidine base. Nucleosides are constituents of the nucleotides that make up nucleic acids.

Nucleotide

Any of a group of compounds consisting of a nucleoside combined with a phosphate group and constituting the units that make up DNA and RNA molecules.

Nucleoside

(biochemistry) an organic molecule in which a nitrogenous heterocyclic base (or nucleobase), which can be either a double-ringed purine or a single-ringed pyrimidine, is covalently attached to a five-carbon pentose sugar (deoxyribose in DNA or ribose in RNA). When the phosphate group is covalently attached to the pentose sugar, it forms a nucleotide.
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Nucleotide

(biochemistry) The monomer constituting DNA or RNA biopolymer molecules. Each nucleotide consists of a nitrogenous heterocyclic base (or nucleobase), which can be either a double-ringed purine or a single-ringed pyrimidine; a five-carbon pentose sugar (deoxyribose in DNA or ribose in RNA); and a phosphate group.

Nucleoside

A type of molecule found in all living organisms, present mostly in chemically combined form as a component of nucleic acids, and also in smaller amounts in free form, consisting of a pentose sugar bound to a purine or pyrimidine base; two types of nucleoside, ribonucleoside and deoxyribonucleoside, are present. The most common bases present in nucleosides are adenine, cytosine, uracil, guanine, and thymine, and to a lesser extent hypoxanthine and other bases are found. The most commmon ribonucleosides composed from these bases are called adenosine, cytidine, uridine, and guanosine. The forms esterified with orthophosphoric at the 5-position of the pentose are called nucleotides. The nucleotides form the monomer units which are combined into DNA and RNA, which carry the genetic information required for reproduction in all known organisms.

Nucleotide

A phosphate ester of a nucleoside; one of the monomeric components of DNA or RNA.

Nucleoside

A glycoside formed by partial hydrolysis of a nucleic acid

Nucleotide

A phosphoric ester of a nucleoside; the basic structural unit of nucleic acids (DNA or RNA)

What is Nucleoside?

A nucleoside is an organic molecule in nature; it comprises of a five carbon sugar attached to a nitrogenous base. The nitrogenous base can be any nitrogenous base depending upon the kind of nucleoside to be developed. The most common sort of nitrogenous bases used as a building block of the nucleoside is adenine, guanine, cytosine, thymine, etc. A nucleoside can be created into nucleotide by simply attaching one or more phosphate groups to it. Nucleoside analogs are very much important and famous regarding their usage in medicines. They work as anticancer and antiviral agents too.

What is Nucleotide?

Nucleotides are the organic molecules that are considered to be the simplest functional unit of RNA and DNA. They are the building blocks of RNA and DNA. Nucleotides are composed of 5 carbon sugar attached to a nitrogenous base and a phosphate group as well. At least presence of single phosphate group is necessary for a nucleotide which makes it nucleotide from nucleoside. There can be as many as required. The nucleoside can be converted into nucleotide by simply adding a phosphate group to the nucleoside.

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