Difference Wiki

Frontline Plus vs. Frontline Gold: What's the Difference?

Edited by Aimie Carlson || By Harlon Moss || Published on February 3, 2024
Frontline Plus is a flea and tick treatment with two active ingredients, while Frontline Gold includes a third ingredient for faster and more effective pest control.

Key Differences

Frontline Plus is a well-known flea and tick preventative for pets, using two key ingredients, fipronil and (S)-methoprene, to kill adult fleas, flea eggs, and ticks. Frontline Gold, on the other hand, enhances this formula by adding a third ingredient, pyriproxyfen, which accelerates the killing of fleas and ticks, offering more rapid and comprehensive pest control.
The name "Frontline Plus" signifies an advanced version of the original Frontline formula, implying additional benefits or features. In contrast, "Frontline Gold" suggests a premium or more potent version of the Frontline products, indicating a higher level of efficacy or quality in flea and tick control.
Frontline Plus has been a staple in pet care for effective flea and tick management, offering reliable protection for a month. Frontline Gold, innovating on this, provides not only longer-lasting protection but also faster action against infestations, making it a more powerful choice for pet owners.
The packaging and branding of Frontline Plus are recognizable and trusted among pet owners. Frontline Gold differentiates itself with distinct packaging, emphasizing its enhanced effectiveness and premium status in the flea and tick treatment market.
In terms of application, both Frontline Plus and Frontline Gold are applied topically on pets, but Frontline Gold's formula is designed to spread more quickly across the pet's body, ensuring more efficient and comprehensive coverage against pests.

Comparison Chart

Word Count

Two words, compound noun
Two words, compound noun

Initial Capitalization

Both words start with capital letters
Both words start with capital letters

Word Type

Noun (Frontline) + Adjective (Plus)
Noun (Frontline) + Noun (Gold)

Syllable Count

Three syllables (Front-line Plus)
Three syllables (Front-line Gold)

Language Origin


Frontline Plus and Frontline Gold Definitions

Frontline Plus

A flea and tick treatment for pets.
I use Frontline Plus monthly to protect my dog from fleas.

Frontline Gold

A topical solution incorporating three active ingredients for pest control.
Frontline Gold, with its triple-action formula, provides comprehensive protection.

Frontline Plus

A product in the Frontline range with added effectiveness.
Frontline Plus offers extra protection compared to the regular Frontline.

Frontline Gold

A pet care product for quicker eradication of fleas and ticks.
I switched to Frontline Gold for its rapid results against fleas.

Frontline Plus

A topical treatment for external parasites in animals.
I apply Frontline Plus on my pet's skin for immediate relief from pests.

Frontline Gold

An advanced formula for flea and tick control in pets.
Frontline Gold's fast action keeps my pets safe from ticks.

Frontline Plus

A preventative measure against flea infestations in pets.
Using Frontline Plus has kept my pet flea-free for years.

Frontline Gold

A premium version of Frontline products with enhanced effectiveness.
For severe infestations, I prefer the superior strength of Frontline Gold.

Frontline Plus

A veterinary-recommended pest control solution.
My vet suggested Frontline Plus for my cat's tick problem.

Frontline Gold

A preferred choice for pet owners seeking the highest level of flea prevention.
Veterinarians often recommend Frontline Gold for persistent pest issues.


Can Frontline Plus be used on puppies?

Yes, Frontline Plus can be used on puppies over 8 weeks of age.

How often should Frontline Plus be applied?

Frontline Plus should be applied once a month for continuous protection.

Is Frontline Gold safe for kittens?

Frontline Gold is safe for kittens over 8 weeks old and weighing more than 2 pounds.

Can Frontline Gold be used on pregnant pets?

It's best to consult a vet before using Frontline Gold on pregnant or nursing pets.

What pests does Frontline Plus target?

Frontline Plus targets fleas, ticks, and lice.

Does Frontline Gold have a stronger formula than Frontline Plus?

Yes, Frontline Gold has a stronger and faster-acting formula.

Is Frontline Plus water-resistant?

Yes, Frontline Plus remains effective even after bathing or swimming.

Is Frontline Plus suitable for all breeds of dogs and cats?

Frontline Plus is suitable for most breeds, but it's best to consult a vet for specific concerns.

What is the main purpose of Frontline Plus?

Frontline Plus is used to treat and prevent flea and tick infestations in pets.

How does Frontline Gold differ from Frontline Plus?

Frontline Gold includes an additional ingredient for faster and more effective pest control.

How quickly does Frontline Gold work?

Frontline Gold starts killing fleas within 30 minutes of application.

Does Frontline Gold help in controlling flea infestations in the home?

Frontline Gold can reduce the flea population in the home by treating pets.

Can Frontline Plus be used alongside other medications?

It's advisable to consult a vet before combining Frontline Plus with other medications.

How long does the effectiveness of Frontline Plus last?

The effectiveness of Frontline Plus lasts for up to 30 days.

Is Frontline Gold effective against all life stages of fleas?

Yes, Frontline Gold is effective against adult fleas, larvae, and eggs.

Can Frontline Gold cause side effects in pets?

Some pets may experience temporary irritation at the application site.

Can Frontline Plus treat tick-borne diseases?

While Frontline Plus kills ticks, it doesn't treat diseases transmitted by them.

Is Frontline Gold effective against American dog ticks?

Yes, Frontline Gold is effective against American dog ticks and other tick species.

How is Frontline Plus applied to pets?

Frontline Plus is applied topically to the pet's skin, typically between the shoulder blades.

Can Frontline Gold be used on a pet with sensitive skin?

For pets with sensitive skin, consult a vet before using Frontline Gold.
About Author
Written by
Harlon Moss
Harlon is a seasoned quality moderator and accomplished content writer for Difference Wiki. An alumnus of the prestigious University of California, he earned his degree in Computer Science. Leveraging his academic background, Harlon brings a meticulous and informed perspective to his work, ensuring content accuracy and excellence.
Edited by
Aimie Carlson
Aimie Carlson, holding a master's degree in English literature, is a fervent English language enthusiast. She lends her writing talents to Difference Wiki, a prominent website that specializes in comparisons, offering readers insightful analyses that both captivate and inform.

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