Difference Wiki

Amphetamine vs. Methylphenidate: What's the Difference?

Edited by Huma Saeed || By Sumera Saeed || Updated on October 4, 2023
Amphetamine is a central nervous system stimulant, often used to treat ADHD and narcolepsy. Methylphenidate, also a stimulant, is primarily prescribed for ADHD.

Key Differences

Amphetamine, known for its stimulant properties, is frequently utilized in medications for attention deficit hyperactivity disorder (ADHD) and narcolepsy. Methylphenidate, on the other hand, is another stimulant specifically designed for the treatment of ADHD and is best known by its brand name, Ritalin.
Sumera Saeed
Oct 03, 2023
The mechanism of action for both drugs is somewhat similar in that they both affect neurotransmitter levels in the brain. However, Amphetamine works primarily by releasing stored neurotransmitters, while Methylphenidate primarily inhibits their reuptake, leading to increased levels in the synapse.
Sumera Saeed
Oct 03, 2023
Both medications can be effective for managing ADHD, but they have distinct pharmacological profiles and potential side effects. While Amphetamine products might include names like Adderall or Evekeo, Methylphenidate can be found under names like Ritalin or Concerta.
Sumera Saeed
Oct 03, 2023
Despite their therapeutic applications, both substances carry the risk of misuse and dependency. It's crucial for physicians to monitor usage and for patients to use Amphetamine and Methylphenidate strictly as prescribed.
Sumera Saeed
Oct 03, 2023

Comparison Chart

Primary Uses

ADHD, narcolepsy
ADHD
Sumera Saeed
Oct 03, 2023
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Mechanism of Action

Releases stored neurotransmitters
Inhibits neurotransmitter reuptake
Sumera Saeed
Oct 03, 2023

Common Brand Names

Adderall, Evekeo
Ritalin, Concerta
Sumera Saeed
Oct 03, 2023

Chemical Structure

Beta-methylated phenethylamine
Phenethylamine derivative
Sumera Saeed
Oct 03, 2023

Dependency Potential

Potential for misuse/dependency
Potential for misuse/dependency
Sara Rehman
Oct 03, 2023

Amphetamine and Methylphenidate Definitions

Amphetamine

A central nervous system stimulant used to treat ADHD and narcolepsy.
The doctor prescribed Amphetamine to help with her narcolepsy symptoms.
Sumera Saeed
Oct 03, 2023
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Methylphenidate

A drug affecting neurotransmitter activity in the brain.
The effects of Methylphenidate allow for increased focus in users.
Janet White
Oct 03, 2023

Amphetamine

A drug that can elevate mood and increase energy.
Some people misuse Amphetamine for its euphoric effects.
Huma Saeed
Oct 03, 2023

Methylphenidate

A stimulant primarily prescribed for ADHD.
Methylphenidate helped him manage his ADHD symptoms during school.
Sara Rehman
Oct 03, 2023

Amphetamine

A medication impacting neurotransmitter levels in the brain.
As an Amphetamine user, he noticed improved concentration.
Sumera Saeed
Oct 03, 2023

Methylphenidate

A substance with a risk of misuse and potential dependency.
Like many stimulants, Methylphenidate should be used cautiously and under supervision.
Janet White
Oct 03, 2023

Amphetamine

A substance with potential for dependency if misused.
It's essential to take Amphetamine only as prescribed to avoid addiction.
Sumera Saeed
Oct 03, 2023

Methylphenidate

A medication increasing synaptic neurotransmitter levels.
Through Methylphenidate, neurotransmitter reuptake is inhibited, helping brain function.
Harlon Moss
Oct 03, 2023

Amphetamine

A psychoactive compound enhancing alertness and focus.
Amphetamine is sometimes misused for its performance-enhancing properties.
Janet White
Oct 03, 2023

Methylphenidate

Known commercially as Ritalin among other names.
His doctor recommended trying Methylphenidate, or Ritalin, for his ADHD.
Harlon Moss
Oct 03, 2023

Amphetamine

A synthetic compound, C9H13N, that occurs as a racemic mixture of two stereoisomers or as one of its stereoisomers (especially dextroamphetamine), derivatives (such as methamphetamine), or salts. Amphetamine acts as a central nervous system stimulant, and various formulations are used in the medical treatment of certain conditions (such as attention deficit hyperactivity disorder) and illegally as stimulants.
Sumera Saeed
Jun 16, 2019

Methylphenidate

A drug, C14H19NO2, chemically related to amphetamine, that acts as a mild stimulant of the central nervous system and is used in its hydrochloride form to treat attention deficit hyperactivity disorder and narcolepsy.
Sumera Saeed
Jun 16, 2019

Amphetamine

The racemic freebase of 1-phenylpropan-2-amine; an equal parts mixture of levoamphetamine and dextroamphetamine in their pure amine forms.
Sumera Saeed
Jun 16, 2019

Methylphenidate

(medicine) A stimulant used to treat attention deficit hyperactivity disorder and narcolepsy, better known by the trade name Ritalin
Sumera Saeed
Jun 16, 2019

Amphetamine

(informal) Any mixture of the two amphetamine enantiomers, dextroamphetamine and levoamphetamine.
Sumera Saeed
Jun 16, 2019

Methylphenidate

Central nervous system stimulant (trade name Ritalin) used in the treatment of narcolepsy in adults and attention deficit disorder in children
Sumera Saeed
Jun 16, 2019

Amphetamine

Referring to a substituted amphetamine; a member of the amphetamine class of chemicals.
Sumera Saeed
Jun 16, 2019

FAQs

Are Amphetamine and Methylphenidate stimulant medications?

Yes, both Amphetamine and Methylphenidate are stimulant medications.
Sumera Saeed
Oct 04, 2023

Is Methylphenidate utilized to manage ADHD?

Yes, Methylphenidate is often utilized in managing ADHD.
Sumera Saeed
Oct 04, 2023

Is Methylphenidate the generic name for Ritalin?

Yes, Methylphenidate is the generic name for the brand drug Ritalin.
Aimie Carlson
Oct 04, 2023

How is Amphetamine administered?

Amphetamine is most commonly administered orally, in either tablet or capsule form.
Harlon Moss
Oct 04, 2023

Can both Amphetamine and Methylphenidate be addictive?

Yes, both Amphetamine and Methylphenidate have the potential for abuse and addiction.
Harlon Moss
Oct 04, 2023

Is Amphetamine used in the treatment of narcolepsy?

Yes, Amphetamine is sometimes used in the treatment of narcolepsy.
Sara Rehman
Oct 04, 2023

What is the typical dosage form of Methylphenidate?

Methylphenidate is available in various forms, including oral tablets and capsules.
Sumera Saeed
Oct 04, 2023

Can Methylphenidate be used in adults?

Yes, Methylphenidate is prescribed to adults for ADHD and sometimes for narcolepsy.
Harlon Moss
Oct 04, 2023

Are there non-stimulant alternatives to Amphetamine for treating ADHD?

Yes, non-stimulant medications like Atomoxetine are available for treating ADHD.
Janet White
Oct 04, 2023

Can individuals with a history of heart problems take Methylphenidate?

Individuals with heart issues should consult their doctor before taking Methylphenidate due to potential risks.
Harlon Moss
Oct 04, 2023

Are there long-term side effects of using Amphetamine?

Yes, long-term use of Amphetamine can have side effects, including heart issues and mental health effects.
Harlon Moss
Oct 04, 2023

Can children be prescribed Methylphenidate?

Yes, Methylphenidate can be prescribed to children, typically over the age of 6, for ADHD.
Sara Rehman
Oct 04, 2023

What are popular brand names that use Amphetamine?

Popular brands like Adderall and Dexedrine contain Amphetamine.
Sumera Saeed
Oct 04, 2023

Can Amphetamine impact mental health?

Yes, Amphetamine can impact mental health, potentially causing anxiety, agitation, and other issues.
Sara Rehman
Oct 04, 2023

How does Methylphenidate affect the central nervous system?

Methylphenidate affects neurotransmitters in the brain, which can enhance concentration and control behavior.
Janet White
Oct 04, 2023

What is Amphetamine commonly prescribed for?

Amphetamine is commonly prescribed to treat Attention Deficit Hyperactivity Disorder (ADHD).
Huma Saeed
Oct 04, 2023

Can Amphetamine be used recreationally?

While it is a prescription medication, Amphetamine can be used recreationally, which is illegal and dangerous.
Sara Rehman
Oct 04, 2023

What are the common side effects of Methylphenidate?

Common side effects of Methylphenidate include insomnia, decreased appetite, and possible increases in blood pressure.
Aimie Carlson
Oct 04, 2023

Is Amphetamine effective in improving focus?

Yes, Amphetamine is known to enhance focus and attention, particularly in individuals with ADHD.
Sumera Saeed
Oct 04, 2023

What precautions are necessary when taking Methylphenidate?

Taking Methylphenidate requires monitoring for side effects, adhering to dosage guidelines, and avoiding certain activities like driving if feeling drowsy.
Sumera Saeed
Oct 04, 2023
About Author
Written by
Sumera Saeed
Sumera is an experienced content writer and editor with a niche in comparative analysis. At Diffeence Wiki, she crafts clear and unbiased comparisons to guide readers in making informed decisions. With a dedication to thorough research and quality, Sumera's work stands out in the digital realm. Off the clock, she enjoys reading and exploring diverse cultures.
Edited by
Huma Saeed
Huma is a renowned researcher acclaimed for her innovative work in Difference Wiki. Her dedication has led to key breakthroughs, establishing her prominence in academia. Her contributions continually inspire and guide her field.

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