Prokaryotic DNA Replication vs. Eukaryotic DNA Replication
Key Differences
Comparison Chart
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Time Taken
Takes Place At
Rate of Base Pairs
Nucleotide
What is Prokaryotic DNA Replication?
Prokaryotic DNA replication is the process through which DNA of prokaryotic cell reproduce itself. It occurs in the cytoplasm of the cell because cell does not have a definite nucleus in it. Origin of prokaryotic DNA replication is single. In prokaryotic DNA replication, replication occurs at one point. Prokaryotic DNA replication has a single origin. Origin of replication is formed of 150-200 nucleotides. The prokaryotic chromosome has only one replication, and one replication bubble is formed during prokaryotic DNA replication. In this length of Okazaki fragments are 1000-2000 nucleotides. Replication is very fast and rapid as about 2000 base pairs per second. DNA polymerase 3 carries out initiation and elongation as well. DNA repair and filling are performed by DNA polymerase 1. RNA primer is also removed by DNA polymerase 1. DNA gyrase is needed.
What is Eukaryotic DNA Replication?
Eukaryotic DNA replication is the process through which DNA of eukaryotic cell reproduce itself. It occurs inside the nucleus of the cell because the cell has a definite nucleus in it. Origin of eukaryotic DNA replication is multiple. In eukaryotic DNA replication, replication occurs at many points. Origin of replication is formed of 150 nucleotides. Many replication forks are formed in each replicating DNA. Eukaryotic DNA have a large number of replications (50,000 or more), but it is not sudden. Okazaki fragments are short (100-200) nucleotides long. Replication in eukaryotes is slower than in prokaryotes; it is 100 base pairs per second. DNA polymerase α initiate the replication process, whereas elongation is carried out by DNA polymerase δ and ε. RNA primer in eukaryotic replication is removed by DNA polymerase β. One thing to be noted here is that DNA gyrase is not needed in it.
