Difference Between G1 Phase vs. G2 Phase

Main Difference

Division or reproduction is a basic need and function of a cell. The division of cell is of two types, mitosis, and meiosis. This division further has sub-steps or stages, one of these steps is interphase in which G1 phase and G2 phase are also included. G1 phase is also known as Gap 1 phase. It is the first sub-phase in the interphase of the cell cycle that is seen in eukaryotic cell division. In this phase, messenger RNA (mRNA) and proteins are synthesized in the cell for the preparation of mitosis. G1 phase is the longest phase of the cell cycle, whereas G2 phase or Gap 2 phase is the second sub-phase or stage of interphase in the cell cycle that further proceeds to mitosis. G2 phase follows the proper completion of S phase of the cell cycle during which the DNA of a cell is replicated. G2 phase is shorter as compared to G1 phase, and it further leads to prophase of mitosis.

Comparison Chart

G1 PhaseG2 Phase
Interphase StepG1 phase is also known as Gap 1 phase, and it is the first sub-step in interphase of the cell cycle.G2 phase is also known as Gap 2 phase, and it is the second sub-step in interphase of the cell cycle.
Time TakenG1 phase is a long process.G2 phase is a shorter process as compared to G1 phase.
Leads ToG1 phase leads to S-phase.G2 phase indicates the successive completion of S phase.
OrganellesIn G1 phase, there is an increase in the size of the cell but the organelle does not increase in number.In G2 phase cell size increases in which nucleus also grow, almost all the cell organelles increase in number.
Main FunctionIn G1 phase, synthesis of useful RNAs and proteins (histone) that are required for the synthesis of DNA and another process in the cell occur here.In G2 phase, RNAs and proteins that are required for spindle formation are synthesized.

What is G1 Phase?

G1 phase is also known as Gap 1 phase. It is the first sub-step in interphase of the cell cycle. It is a long process as compared to G2 phase. In G1 phase, there is an increase in the size of the cell but the organelle does not increase in number. Synthesis of useful RNAs and proteins (histone) that are required for the synthesis of DNA and another process in the cell occur in this state. G1 phase next leaders to the S phase. The average time for the G1 phase is up to 18 hours that may vary from cell to cell. Moreover, G1 phase has many factors upon which it depends. These factors are also called growth factors such as the environment of cell, temperature, supply of nutrients, proteins and amino acids, etc. The optimum temperature for proper growth is 98.6 degrees F (37 degrees C). Regulation of G1 phase is controlled by cell cycle control system that regulates the timing and increases the coordination.

What is G2 Phase?

G2 phase is also known as Gap 2 phase. It is the second sub-step in interphase of the cell cycle. It is a shorter process as compared to G1 phase. In G2 phase, there is rapid cell growth and protein synthesis. This phase is not the necessary part of the cell cycle, but it allows the cell to be fully prepared for mitosis. G2 phase indicates the successive completion of S phase, in which DNA replication takes place. Cell size increases in which nucleus also grow, almost all the cell organelles increases in number. RNAs and proteins that are required for spindle formation are synthesized in this phase. G2 phase ends as prophase (the first step in mitosis), and it is regulated by the cell itself as it all depend upon genetic information of the cell.

G1 Phase vs. G2 Phase

  • G1 phase is also known as Gap 1 phase, and it is the first sub-step in interphase of the cell cycle, whereas G2 phase is also known as Gap 2 phase and it is the second sub-step in interphase of the cell
  • G1 phase is a long process whereas, G2 phase is a shorter process as compared to G1 phase.
  • G1 phase leads to S-phase, whereas G2 phase indicates the successive completion of S phase
  • In G1 phase, there is an increase in the size of the cell but the organelle does not increase in number, on the other hand, in G2 phase cell size increases in which nucleus also grow, almost all the cell organelles increase in number.
  • In G1 phase, synthesis of useful RNAs and proteins (histone) that are required for the synthesis of DNA and another process in the cell occur here whereas, in G2 phase, RNAs and proteins that are required for spindle formation are synthesized.

Comparison Video

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