Difference Wiki

Ergosterol vs. Cholesterol: What's the Difference?

Edited by Huma Saeed || By Sumera Saeed || Published on December 22, 2023
Ergosterol is a sterol found in fungi and some protozoa, crucial for their cell membrane integrity and vitamin D2 synthesis, whereas cholesterol is a sterol in animal cells, essential for cell membrane stability and as a precursor for steroid hormones.

Key Differences

Ergosterol plays a key role in maintaining the structural integrity of fungal cell membranes. Cholesterol serves a similar structural role in animal cell membranes, contributing to their fluidity and integrity.
Sumera Saeed
Dec 22, 2023
Ergosterol is predominantly found in fungi and some protozoa. In contrast, cholesterol is a major component in the cell membranes of animals, including humans, and is absent in plants and fungi.
Sumera Saeed
Dec 22, 2023
Ergosterol is vital for the function and growth of fungal cells and is a precursor to vitamin D2. Cholesterol is essential for the production of steroid hormones, bile acids, and vitamin D3 in animals.
Huma Saeed
Dec 22, 2023
Ergosterol is targeted by antifungal medications, as its disruption affects fungal survival. Cholesterol, while essential, can contribute to health issues like atherosclerosis when levels are unbalanced in humans.
Sumera Saeed
Dec 22, 2023
Humans do not produce ergosterol, and it is typically not significant in their diet. Cholesterol, however, is synthesized in the liver and can also be consumed through animal-based foods.
Sumera Saeed
Dec 22, 2023
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Comparison Chart

Found In

Fungi and some protozoa
Animal cells
Sumera Saeed
Dec 22, 2023

Biological Role

Maintains fungal cell membrane integrity
Stabilizes animal cell membranes
Sumera Saeed
Dec 22, 2023

Key Functions

Precursor to vitamin D2
Precursor to steroid hormones, vitamin D3
Sumera Saeed
Dec 22, 2023

Health Implications

Target for antifungal drugs
Linked to cardiovascular diseases in excess
Janet White
Dec 22, 2023

Dietary Source

Not significant in human diet
Found in animal-based foods
Aimie Carlson
Dec 22, 2023
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Ergosterol and Cholesterol Definitions

Ergosterol

A sterol component in fungal cell membranes.
Ergosterol is essential for fungal cell survival.
Sumera Saeed
Dec 04, 2023

Cholesterol

Produced in the liver and obtained from animal-based foods.
Meat, eggs, and dairy products are rich in cholesterol.
Janet White
Dec 04, 2023

Ergosterol

A target for antifungal medications.
Antifungal drugs work by inhibiting ergosterol synthesis.
Sumera Saeed
Dec 04, 2023

Cholesterol

A precursor for steroid hormones and vitamin D3.
Cholesterol is vital for synthesizing hormones like estrogen and testosterone.
Aimie Carlson
Dec 04, 2023

Ergosterol

A precursor to vitamin D2 in fungi.
Sunlight exposure converts ergosterol to vitamin D2 in mushrooms.
Harlon Moss
Dec 04, 2023

Cholesterol

A substance linked to cardiovascular health.
High cholesterol levels can increase heart disease risk.
Harlon Moss
Dec 04, 2023

Ergosterol

A biological molecule distinct to fungi.
Ergosterol's presence helps distinguish fungi from other organisms.
Janet White
Dec 04, 2023

Cholesterol

A sterol in animal cell membranes for stability.
Cholesterol is a key component of human cell membranes.
Huma Saeed
Dec 04, 2023

Ergosterol

A compound contributing to the integrity of fungal cells.
Ergosterol is crucial for maintaining the fungal cell structure.
Aimie Carlson
Dec 04, 2023

Cholesterol

A molecule balancing fluidity in animal cell membranes.
Cholesterol contributes to the optimal function of cell membranes.
Harlon Moss
Dec 04, 2023

Ergosterol

A crystalline sterol, C28H43OH, synthesized by yeast from sugars or derived from ergot and converted to vitamin D2 when exposed to ultraviolet radiation.
Sumera Saeed
Nov 30, 2023

Cholesterol

A white crystalline substance, C27H45OH, that is found in animal tissues and various foods and is important as a constituent of cell membranes and a precursor to steroid hormones. Cholesterol is normally synthesized by the liver and is transported through the bloodstream by different types of lipoproteins, two of which (HDL and LDL) are routinely measured in blood tests.
Sumera Saeed
Nov 30, 2023

Ergosterol

The steroid precursor of vitamin D2. It is found in cell membranes of fungi, and is their functional equivalent of cholesterol. It is also found in the membranes of some protists.
Sumera Saeed
Nov 30, 2023

Cholesterol

(biochemistry) A sterol lipid synthesized by the liver and transported in the bloodstream to the membranes of all animal cells; it plays a central role in many biochemical processes and, as a lipoprotein that coats the walls of blood vessels, is associated with cardiovascular disease.
Sumera Saeed
Nov 30, 2023

Ergosterol

A plant sterol that is converted into vitamin D by ultraviolet radiation.
Sumera Saeed
Nov 30, 2023

Cholesterol

The level of cholesterol in the body.
Improve your cholesterol; lower your cholesterol
Sumera Saeed
Nov 30, 2023

Ergosterol

A plant sterol that is converted into vitamin D by ultraviolet radiation
Sumera Saeed
Nov 30, 2023

Cholesterol

An animal sterol that is normally synthesized by the liver; the most abundant steroid in animal tissues
Sumera Saeed
Nov 30, 2023

FAQs

What is ergosterol?

Ergosterol is a sterol found in the cell membranes of fungi and some protozoa.
Sumera Saeed
Dec 22, 2023

What is cholesterol?

Cholesterol is a sterol essential for the structure and function of animal cell membranes.
Huma Saeed
Dec 22, 2023

What is the role of ergosterol in fungi?

Ergosterol maintains the integrity and fluidity of fungal cell membranes.
Sumera Saeed
Dec 22, 2023

What is the role of cholesterol in humans?

Cholesterol stabilizes cell membranes and is a precursor for hormones and vitamin D3.
Aimie Carlson
Dec 22, 2023

Do antifungal drugs target ergosterol?

Yes, many antifungal drugs target the synthesis or function of ergosterol in fungi.
Aimie Carlson
Dec 22, 2023

Where is cholesterol found?

Cholesterol is found in animal cells and is absent in plants and fungi.
Janet White
Dec 22, 2023

Can humans produce cholesterol?

Yes, the human liver synthesizes cholesterol.
Sumera Saeed
Dec 22, 2023

How does cholesterol affect human health?

Balanced cholesterol levels are vital for health, but excess can lead to heart disease.
Sumera Saeed
Dec 22, 2023

Where is ergosterol found?

Ergosterol is primarily found in fungi and some protozoan species.
Sumera Saeed
Dec 22, 2023

Is ergosterol in the human diet?

Ergosterol is not typically significant in the human diet.
Janet White
Dec 22, 2023

Can humans produce ergosterol?

No, humans do not produce ergosterol.
Janet White
Dec 22, 2023

How does ergosterol affect human health?

Ergosterol itself is not significant in human health but is a target for antifungal drugs.
Janet White
Dec 22, 2023

Are ergosterol and cholesterol structurally similar?

They are both sterols, but they have different chemical structures.
Aimie Carlson
Dec 22, 2023

What happens when ergosterol is inhibited?

Inhibiting ergosterol in fungi disrupts their cell membrane and can kill the fungal cells.
Sumera Saeed
Dec 22, 2023

What are the sources of dietary cholesterol?

Dietary cholesterol comes primarily from meat, dairy products, and eggs.
Janet White
Dec 22, 2023

Is ergosterol a vitamin D precursor?

Yes, ergosterol can be converted into vitamin D2 with sunlight exposure.
Sumera Saeed
Dec 22, 2023

Can cholesterol levels be too high?

Yes, high cholesterol levels can increase the risk of cardiovascular diseases.
Aimie Carlson
Dec 22, 2023

Can cholesterol be beneficial?

Cholesterol is essential for many body functions but needs to be balanced.
Sumera Saeed
Dec 22, 2023

Is cholesterol in the human diet?

Cholesterol is found in animal-based foods and can be part of the human diet.
Harlon Moss
Dec 22, 2023

How is ergosterol different from plant sterols?

Ergosterol is specific to fungi, while plants have their unique sterols.
Harlon Moss
Dec 22, 2023
About Author
Written by
Sumera Saeed
Sumera is an experienced content writer and editor with a niche in comparative analysis. At Diffeence Wiki, she crafts clear and unbiased comparisons to guide readers in making informed decisions. With a dedication to thorough research and quality, Sumera's work stands out in the digital realm. Off the clock, she enjoys reading and exploring diverse cultures.
Edited by
Huma Saeed
Huma is a renowned researcher acclaimed for her innovative work in Difference Wiki. Her dedication has led to key breakthroughs, establishing her prominence in academia. Her contributions continually inspire and guide her field.

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