Difference Wiki

Adrenal Cortex vs. Adrenal Medulla: What's the Difference?

Edited by Janet White || By Harlon Moss || Updated on October 29, 2023
The adrenal cortex is the outer part of the adrenal gland that produces steroid hormones; the adrenal medulla is the inner part that produces adrenaline.

Key Differences

The adrenal cortex is the outer layer of the adrenal gland, and it produces a range of steroid hormones including cortisol, aldosterone, and androgens. The adrenal medulla, on the other hand, is the innermost part of the gland, and it produces catecholamines, such as adrenaline and noradrenaline.
While the adrenal cortex is vital for maintaining fluid and electrolyte balance through the production of aldosterone, the adrenal medulla plays a key role in the body’s fight-or-flight response by releasing adrenaline. These two components of the adrenal gland work together to help the body respond to stress.
The hormones produced by the adrenal cortex have effects on nearly every tissue in the body and are vital for life. In contrast, while the hormones produced by the adrenal medulla are important for responding to stress, they are not essential for life. Both the adrenal cortex and adrenal medulla are regulated by different mechanisms and have different functions within the body.
The adrenal cortex is involved in the production of hormones that regulate metabolism, immune system function, and other vital processes. The adrenal medulla, however, functions mainly as a part of the sympathetic nervous system, releasing adrenaline and noradrenaline in response to stress. Both the adrenal cortex and adrenal medulla are essential components of the adrenal gland, playing crucial roles in maintaining homeostasis within the body.

Comparison Chart

Location

Outer layer of the adrenal gland
Inner part of the adrenal gland
ADVERTISEMENT

Tissue Type

Glandular tissue
Neural tissue

Hormones Produced

Corticosteroids and androgens
Adrenaline and noradrenaline

Main Functions

Regulates metabolism, immune system, and salt and water balance
Prepares the body for "fight or flight" response

Response to Stress

Responds slowly by releasing corticosteroids
Responds quickly by releasing adrenaline and noradrenaline

Adrenal Cortex and Adrenal Medulla Definitions

Adrenal Cortex

The adrenal cortex affects nearly every tissue in the body.
Hormones produced by the adrenal cortex are essential for life.
ADVERTISEMENT

Adrenal Medulla

The adrenal medulla is not vital for life.
While important, the hormones produced by the adrenal medulla are not essential for life.

Adrenal Cortex

The adrenal cortex is regulated by hormonal and neural mechanisms.
The function of the adrenal cortex is critical for overall health and well-being.

Adrenal Medulla

The adrenal medulla initiates the fight-or-flight response.
The adrenal medulla helps the body respond to stressful situations.

Adrenal Cortex

The adrenal cortex is the outer layer of the adrenal gland.
The adrenal cortex plays a key role in the body's response to stress.

Adrenal Medulla

The adrenal medulla is the inner part of the adrenal gland.
The adrenal medulla is responsible for producing hormones that help the body respond to stress.

Adrenal Cortex

The adrenal cortex produces steroid hormones.
The adrenal cortex plays a crucial role in hormone production.

Adrenal Medulla

The adrenal medulla is part of the sympathetic nervous system.
The adrenal medulla works with the sympathetic nervous system to regulate the body's response to stress.

Adrenal Cortex

The adrenal cortex is vital for maintaining fluid and electrolyte balance.
The adrenal cortex produces aldosterone, which helps regulate blood pressure.

Adrenal Medulla

The adrenal medulla produces catecholamines.
Adrenaline and noradrenaline are produced in the adrenal medulla.

FAQs

What hormones does the adrenal cortex produce?

The adrenal cortex produces cortisol, aldosterone, and androgens.

What hormones does the adrenal medulla produce?

The adrenal medulla produces adrenaline and noradrenaline.

What is the function of the adrenal cortex?

The adrenal cortex regulates metabolism, immune system function, and more.

What is the adrenal medulla?

The inner part of the adrenal gland that produces catecholamines.

Is the adrenal cortex vital for life?

Yes, the hormones produced by the adrenal cortex are essential for life.

Is the adrenal medulla vital for life?

No, while the hormones produced by the adrenal medulla are important, they are not essential for life.

How is the adrenal cortex regulated?

The adrenal cortex is regulated by hormonal and neural mechanisms.

How is the adrenal medulla regulated?

The adrenal medulla is part of the sympathetic nervous system.

Does the adrenal cortex produce aldosterone?

Yes, the adrenal cortex produces aldosterone.

What is the role of adrenaline?

Adrenaline initiates the fight-or-flight response.

What other hormones does the adrenal cortex produce?

The adrenal cortex also produces androgens.

What is the function of the adrenal medulla?

The adrenal medulla initiates the fight-or-flight response.

Where is the adrenal cortex located?

The adrenal cortex is the outer layer of the adrenal gland.

Does the adrenal medulla produce adrenaline?

Yes, the adrenal medulla produces adrenaline.

What is the role of aldosterone?

Aldosterone helps regulate blood pressure by maintaining fluid and electrolyte balance.

What does the adrenal cortex affect?

The adrenal cortex affects nearly every tissue in the body.

What does the adrenal medulla affect?

The adrenal medulla affects the body's response to stress.

What is the adrenal cortex?

The outer part of the adrenal gland that produces steroid hormones.

Where is the adrenal medulla located?

The adrenal medulla is the innermost part of the adrenal gland.

What other hormones does the adrenal medulla produce?

The adrenal medulla also produces noradrenaline.
About Author
Written by
Harlon Moss
Harlon is a seasoned quality moderator and accomplished content writer for Difference Wiki. An alumnus of the prestigious University of California, he earned his degree in Computer Science. Leveraging his academic background, Harlon brings a meticulous and informed perspective to his work, ensuring content accuracy and excellence.
Edited by
Janet White
Janet White has been an esteemed writer and blogger for Difference Wiki. Holding a Master's degree in Science and Medical Journalism from the prestigious Boston University, she has consistently demonstrated her expertise and passion for her field. When she's not immersed in her work, Janet relishes her time exercising, delving into a good book, and cherishing moments with friends and family.

Trending Comparisons

Popular Comparisons

New Comparisons