Hyphae vs. Pseudohyphae

Key Differences



Comparison Chart
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Occurrence
Shape of Cells
Degree of Cell Separation

Nuclear Division and Septation
Hyphae and Pseudohyphae Definitions
Hyphae
Pseudohyphae
Hyphae
Hyphae
Hyphae
Hyphae vs. Pseudohyphae
Hyphae and pseudohyphae are two types of strands that constitute vegetative structures present in fungi. Hyphae are the elongating, thread-like filaments whereas the pseudohyphae are the newly-dividing cells through budding. The hyphae arise in filamentous fungi while the pseudohyphae arise in the unicellular fungi such as yeast and pleiomorphic fungi, which are in alteration state between filamentous and unicellular forms. The cells of the hyphae are long, thin and highly polarize while the cells of pseudohyphae are ellipsoid-shape. There is no restriction between the cells of hyphae but, hyphae hold septa while the cells of pseudohyphae contain an apparent limitation between them. Nuclear division and septation happen at some expanse in hyphae while in pseudohyphae, nuclear division of pseudohyphae befalls at the point of maximum constriction and the septation befalls at the point of minimum contraction. Cell division in hyphae is apical form. The cell division in pseudohyphae is synchronous. Hyphae may or may not comprise septa, whereas pseudonymous always comprise septa. Hyphae is coenocytic (single-celled, multinuclear) or multicellular, but pseudohyphae are still multicellular. Hyphae do not show budding whereas pseudohyphae do show budding through which it grows continuously. Hyphae are always stationary, whereas pseudohyphae are uses to invade cells by increasing faster and showing some movement.
What are Hyphae?
Hyphae are states as one or more elongating, tubular cells, fungal body and branching filaments that form the mycelium of a fungus. It is the primary vegetative growth type of fungi. Multicellular hyphae are internally dividing by cross walls, septa displaying a chain of the tightly packed cell. Hyphae with septa are known as septate hyphae, and hyphae without septa are known as the non-septic fungi and hyphae are known as aseptate hyphae. The cells of the hyphae are protecting by a rigid cell wall. Small pores on the septa permit the transport of organelles between the adjacent cells of the hypha. The development of the hyphae occurs at the apex. There are several classifications of hyphae according to the form and appearance. Hyphae are modifying according to the function. The apical growth occurs when parts of hyphae move forward. Fungal hyphae form haustoria to captivate nutrients from the substrate. The hyphae present in lichens (fungal-algae associations) are modifying to protect its reproductive structures and makes a large portion of the structure including the formation of attaching packs to a substrate.
What are Pseudohyphae?
Pseudohyphae are a variety of filaments that form during the cell division in newly-dividing cells (pseudomycelia) mostly in polymorphic fungi like Candida spp through budding. Each cell of the pseudohyphae resembles an elongating ellipsoid that’s why it is composing of ellipsoidal and conjoin elongating yeast-like cells. The extent of elongation depends on growth conditions. These cells remain connecting as a chain with constrictions at the site where septa present. Pseudohyphae contain newly dividing cells through budding which continue to adhere as chains and branches as they occur in unicellular fungi such as yeast. The adhering happens at the constricting septation site. Some scientists consider pseudohyphae as an intermediary state between yeast-like cells and true hyphae. Each cell is separating by a prominent restriction site. The pseudohyphae cell division is more synchronous, as each cell in the chain can experience cell division. Therefore, pseudohyphae display a more branch pattern. Pseudohyphae function as in Candida albicans as an aggressive mobile form. It supposes that the pathogenicity of C. albicans is increasing when it is present as pseudomycelium.