Difference Wiki


The main difference between CBD and CBN is that CBD is an abbreviation of cannabidiol whereas CBN is the abbreviation of cannabinol.

Key Differences

CBD is present in the plant naturally whereas CNB forms while aging of the plant.
CBD is the precursor whereas CBN is the metabolite of THC (Tetrahydrocannabinol).
CBD is non-psychoactive whereas CBN is mildly psychoactive in nature.
Samantha Walker
Sep 05, 2023
The chemical formula of CBD is C21H30O2 whereas chemical formula of CBN is C21H26O2.

Comparison Chart


Cannabidiol is a phytocannabinoid and is one of the 113 cannabinoids in the cannabis plant.
Cannabinol is a mildly psychoactive cannabinoid found in minute quantities in cannabis.

Source Plant

In cannabis and hemp plant
More common in the cut plant of cannabis

Psychoactive Property



Indirectly acting on CB1 and CB2
Directly acting on CB1 and CB2

Physical Properties

Formula: C21H30O2 Half-Life: 18 to 32 hrs Solubility: soluble in water
Formula: C21H26O2 Solubility: Insoluble in water, soluble in methanol and ethanol

Side effects

Dry mouth, low blood pressure, drowsiness, lightheadedness
Tiredness, Drowsiness, Dizziness, loss of appetite
Samantha Walker
Sep 05, 2023


Regulator of appetite, used in obesity, pain, inflammation, insomnia, seizures, dystonia, Parkinsonism disease, bipolar disorder, glaucoma
Appetite stimulator, pain, as antibacterial, inflammation, insomnia, seizures, growth of bone cells
Harlon Moss
Sep 05, 2023


Cannabis has numerous cannabinoids, of which tetrahydrocannabinol (TH), Cannabidiol (CBD) and cannabinol (CBN). CBD is the precursor of the THC whereas CBN is the metabolite of THC. CBD is known as a non-psychoactive healing agent whereas CBN is a mildly psychoactive agent. CBD is formed when THC breaks down. When the plant is decarboxylated, heat breaks the molecules which are responsible for the acid molecules integrity, and as a result, CBD has obtained. CBN is also obtained from THC when THC is broken down due to UV light exposure and oxygenation.

CBD and CBN interact with the human endocannabinoid system in different ways. CBD exhibits a little affinity to the CB1 and CB2 receptors which are found in the nervous and immune systems. CBN has a weak affinity to both receptors, but more research is needed to get a clear picture. CBD and CBN are also different from each other in benefits. CBD is not beneficial for the people with sleep problems at low doses so people need a high dose, e.g. 160 mg whereas CBN is very seductive in nature and its small quantity 2.5 mg can cause seductive effect. CBD is an appetite stimulant whereas CBN can suppress appetite in order to reduce obesity. Low doses (40 mg) of CBD are effective to reduce pressure which causes glaucoma whereas CBN is also effective against glaucoma in very small doses. CBD does not cause a feeling of elation whereas CBN produces a feeling of elation.

What is CBD?

Cannabidiol is a chemical of the plant cannabis which is also known as marijuana. Almost 80 chemicals have been extracted from cannabis which is called cannabinoids. Among them, Delta-9-tetrahydrocannabinol is the major active ingredient and CBD makes up almost 40% of cannabis extract. It has numerous uses as a drug. Some commercial products of dietary supplements contain Cannabidiol. People take CBD by mouth for anxiety, schizophrenia, Parkinsonism disease, bipolar disease, dystonia, seizures, and multiple sclerosis. People also use Cannabinol to quit smoking through inhalation.

How does it work?

CBD has antipsychotic effects. But the exact cause of these effects is not clear. It seems to prevent the breakdown of a chemical in the brain that affects mood, pain and mental function. It reduces psychotic symptoms of schizophrenia by breaking off this chemical and enhancing the level in the blood. Cannabidiol might also block a few psychotic effects of THC. It also reduces anxiety and pain.

What is CBN?

Cannabinol or CBN comes from THC. It is a cannabinoid that forms upon the oxygenation, UV light exposure and decomposition of THC. It is most commonly found in aged cannabis plants and rarely on the flowering plant of hemp. A live flowery plant does not contain CBN; it comes on aging. This is also used as a drug. CBN is effective for pain relief as it alters the pain signals that are sent to the brain by the neurons. Its antibacterial use comprises the fighting with MRSA bacteria. It is an infection in which antibiotics are resistant to antibiotics. As it is the byproduct of THC, it has potent anticonvulsive properties. It is currently used as a sedative compound that can help people who suffer from conditions such as anxiety and insomnia disorder. CBN gathers and modulates mesenchymal stem cells and in this way proves effective cannabinoid in creating bone tissues and healing bone fractures. Although it is harmful, all cannabinoids have some side effects in overdose. CBN has tiredness, dizziness, drowsiness, and loss of appetite as unwanted effects. These side effects can be avoided by careful measuring of dose and starting slow.

How does it work?

Cannabinoids are effective in multiple mechanisms of action or pathways. CBN produces a beneficial effect because they can activate multiple biological pathways at once. It may also produce a wider variety of effects through channels separate from CB1 and CB2 receptors.

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