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Bactericidal vs. Bacteriostatic

The main difference between Bactericidal and Bacteriostatic is that the Bactericidal is the type of antibiotic that kills the bacteria, whereas the Bacteriostatic is the type of antibiotic that prevents the further growth of the bacteria.

Key Differences

Bactericidal works for the destruction of bacterial cells, whereas the Bacteriostatic works for the growth prevention of bacterial cells.
Bactericidal causes toxic shock syndrome; Bacteriostatic has a little or no toxic effect.
The action of Bactericidal is not reversible; on the other hand, the action of Bacteriostatic is reversible.
Bactericidal can perform its function by a little number of doses; on the other hand, Bacteriostatic can perform its function only with its high amount of doses.
Aimie Carlson
Mar 11, 2020
Bactericidal is specific only for diseases like endocarditis, and meningitis; on the flip side, Bacteriostatic is specific for the urinary tract infections and gangrene wound infections.
Aimie Carlson
Mar 11, 2020
Bactericidal does not work with the immune system of the host; on the flip side, Bacteriostatic works with the immune system of the host.
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Bactericidal antibiotics mainly work by interfering with the cell wall of bacterial cells; on the other hand, Bacteriostatic works by inhibiting DNA replication and protein synthesis.
Janet White
Mar 11, 2020
Bactericidal causes a decrease in the number of bacterial cells; on the flip side, Bacteriostatic does not cause a decrease in the number of bacterial cells.
The examples of bactericidal are vancomycin and monoglycosidic; on the other hand, the examples of Bacteriostatic are spectinomycin, sulfonamides, etc.
Janet White
Mar 11, 2020

Comparison Chart

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Bactericidal refers to the destruction of the bacterial cell
Bacteriostatic refers to the inhibition of the bacterial cell

Action

Its action is irreversible
Its action is reversible

Working

It works by interacting with the cell wall of the bacterial cell
It works by causing the prevention of DNA replication and protein synthesis
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Immune System of Host

It does not work with the immune system of the host
It works with the immune system of the host
Harlon Moss
Mar 11, 2020

Side Effects

Causes the toxic shock syndrome
Have little or no side effect

Amount of Doses

A little dose can cause its effect
Only a high dose has its effect

Specificity

It is specific for only diseases like endocarditis and meningitis, etc
It is specific for urinary infections, and gangrene wound infections, etc

Examples

It includes Penicillin derivatives, vancomycin, monoglycosidic antibiotics, etc
It includes Tetracycline, spectinomycin, sulfonamides, etc
Aimie Carlson
Mar 11, 2020

Bactericidal and Bacteriostatic Definitions

Bactericidal

A substance or agent that destroys bacteria.
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Bacteriostatic

An agent, such as a chemical or biological material, that inhibits bacterial growth.

Bactericidal

That kills bacteria.

Bacteriostatic

Of or relating to bacteriostasis or a bacteriostat; inhibiting the growth of bacteria without destroying them.

Bactericidal

Of or pertaining to a bactericide.

Bacteriostatic

Of or pertaining to bacteriostasis or a bacteriostat.

Bactericidal

A bactericide.

Bacteriostatic

Causing bacteriostasis; - said of chemical substances, such as certain antibacterial agents.

Bactericidal

Destructive of bacteria.

Bacteriostatic

Of or relating to or causing bacteriostasis

Bactericidal

Preventing infection by inhibiting the growth or action of microorganisms

Bactericidal vs. Bacteriostatic

Bactericidal destroys the bacteria; on the other hand, bacteriostatic inhibits the growth of bacteria. The work of bactericidal is irreversible; on the flip side, the work of bacteriostatic is reversible. Bactericidal causes a decrease in several bacterial cells; on the other hand, bacteriostatic does not cause a decrease in the number of bacterial cells.

Bactericidal antibiotics disrupt the bacterial cell wall; on the other hand, bacteriostatic causes the inhibition of growth of bacteria by preventing DNA replication and other metabolic activities. Bactericidal may cause toxic shock syndromes; on the flip side, bacteriostatic has no little side effects. Bactericidal does not work with the immune system of the host; on the other hand, bacteriostatic causes the immune system of the host to prevent the growth of the bacterial cells.

Bactericidal mainly use in diseases like meningitis and endocarditis; on the flip side, bacteriostatic usually use in diseases of the urinary tract and gangrene wound infections. The examples of bactericidal are penicillin, vancomycin, monoglycosidic antibiotics, whereas the examples of bacteriostatic are streptomycin, tetracycline, chloramphenicol.

What is Bactericidal?

Bactericidal is the special type of antibiotic that works by killing the bacterial cells. As it involves the destruction of bacterial cells, it causes a decrease in the number of bacterial cells. That’s why the function of bactericidal antibiotics is not reversible. It destroys bacterial cells.

This destruction of bacterial cells causes toxic shock syndromes in the host cell. It usually does not work with the immune system of the host cell. This antibiotic is useful even in its little amount. The concentration of the bactericidal antibiotic drug to kill the bacterial cell is express in the MBC term. This type of drug is specific for some diseases like meningitis, etc.

It destroys bacterial cells by interfering and penetrating the cell wall of bacteria. This type of drug has a little preference because of its side effects, and bacteriostatic more commonly used in this process. Bactericidal contributes or causes the irreversible death of bacterial cells. It not only affects the cell wall of bacteria but also interacts with the proteins, lipids, carbohydrates, and enzymes of bacterial cells.

Bactericidal does not cause any other effects on bacterial cells rather than the direct treatment of bacterial cell death. The examples of bactericidal include derivatives of the penicillin, vancomycin, and monoglycosidic antibiotics.

What is Bacteriostatic?

Bacteriostatic is a special type of antibiotic that deals with the inhibition of bacterial cell growth. As it is only involved in the prevention of bacterial cell growth, it does not cause a decrease in the number of individual bacterial cells. That’s why the function of bacteriostatic is reversible. It does not destroy the cell.

This type of antibiotic has little or no side effects in the host cells. It completes its work by working with the immune system of the host cells. Bacteriostatic drugs are useful in the function when there is a large number of drugs used. The concentration of bacteriostatic drugs to stop the growth of bacterial cells is expressed in the MIC term.

It is specific for urinary tract infections and gangrene wound infections. It performs its function by preventing DNA replication and protein synthesis. Bacteriostatic because of its little side effects are more commonly used. It causes reversible actions that can get to its normal functions after the conditions removed.

It not only prevents the growth of bacterial cells but also causes the prevention of the reproduction of the bacterial cells. It used to prevent the bacterial cells from dividing into daughter cells by binary fission. The most common examples of bacteriostatic drugs are tetracycline, spectinomycin, chloramphenicol, and sulfonamides, etc.

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