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Urea vs. Uric Acid: What's the Difference?

Edited by Sumera Saeed || By Huma Saeed || Published on December 6, 2023
Urea is a waste product formed from the breakdown of proteins, commonly excreted in urine, while uric acid is produced from the breakdown of purines and can accumulate in the body, leading to gout.

Key Differences

Urea is formed in the liver as a waste product of protein metabolism and is highly soluble in water. While, uric acid is produced from the metabolism of purines, found in many foods, and is less soluble in water, which can lead to its crystallization in the body.
Huma Saeed
Dec 06, 2023
The human body excretes urea primarily through urine, making it a major component of urine. However, uric acid is also excreted through urine, but its lower solubility can cause it to accumulate in the body, potentially leading to conditions like gout.
Huma Saeed
Dec 06, 2023
Elevated levels of urea in the blood can indicate kidney dysfunction. High levels of uric acid can lead to gout and are associated with other health conditions like kidney stones and renal failure.
Sumera Saeed
Dec 06, 2023
Urea serves primarily as a vehicle for nitrogen excretion. Uric acid, apart from being a waste product, also has antioxidant properties.
Aimie Carlson
Dec 06, 2023
Urea is used in medical diagnostics, and in various industrial applications, including fertilizers and cosmetics. Uric acid’s significance lies mainly in its medical implications, particularly in diagnosing and managing gout.
Huma Saeed
Dec 06, 2023
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Comparison Chart

Formation

From protein metabolism.
From purine metabolism.
Huma Saeed
Dec 06, 2023

Excretion

Primarily through urine, highly soluble.
Through urine, less soluble, can accumulate.
Huma Saeed
Dec 06, 2023

Health Implications

Indicator of kidney function.
Can lead to gout, kidney stones.
Huma Saeed
Dec 06, 2023

Biological Role

Nitrogen excretion.
Waste product with antioxidant properties.
Aimie Carlson
Dec 06, 2023

Uses

Medical diagnostics, fertilizers, cosmetics.
Medical diagnosis and management of gout.
Harlon Moss
Dec 06, 2023
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Urea and Uric Acid Definitions

Urea

Used as a fertilizer due to its high nitrogen content.
Urea-based fertilizers are popular in agriculture.
Aimie Carlson
Nov 21, 2023

Uric Acid

Excreted through the kidneys and urine.
Kidney function affects uric acid excretion.
Sumera Saeed
Nov 21, 2023

Urea

A nitrogen-containing compound produced in the liver.
Urea is synthesized in the liver from ammonia.
Sumera Saeed
Nov 21, 2023

Uric Acid

A product of purine metabolism in the body.
Uric acid levels can rise with high purine diets.
Huma Saeed
Nov 21, 2023

Urea

A major organic component of human urine.
Urine analysis often measures urea levels.
Harlon Moss
Nov 21, 2023

Uric Acid

Can crystallize in joints, causing gout.
Elevated uric acid is a primary cause of gout.
Huma Saeed
Nov 21, 2023

Urea

Employed in cosmetics for its moisturizing properties.
This lotion contains urea for better skin hydration.
Harlon Moss
Nov 21, 2023

Uric Acid

Associated with kidney stones and renal failure.
High uric acid levels can lead to kidney stones.
Huma Saeed
Nov 21, 2023

Urea

Utilized in medical diagnostics.
Blood urea nitrogen tests assess kidney function.
Aimie Carlson
Nov 21, 2023

Uric Acid

Acts as an antioxidant in the human body.
Uric acid has natural antioxidant properties.
Huma Saeed
Nov 21, 2023

Urea

A water-soluble compound, CO(NH2)2, that is the major nitrogenous end product of protein metabolism and is the chief nitrogenous component of the urine in mammals and certain other animals. Also called carbamide.
Huma Saeed
Nov 19, 2023

Urea

A water-soluble organic compound, CO(NH2)2, formed by the metabolism of proteins and excreted in the urine.
Huma Saeed
Nov 19, 2023

Urea

Any N-substituted derivative of urea, with the general formula (R1R2N)CO(NR3R4).
Huma Saeed
Nov 19, 2023

Urea

A very soluble crystalline body which is the chief constituent of the urine in mammals and some other animals. It is also present in small quantity in blood, serous fluids, lymph, the liver, etc.
Huma Saeed
Nov 19, 2023

Urea

The chief solid component of mammalian urine; synthesized from ammonia and carbon dioxide and used as fertilizer and in animal feed and in plastics
Huma Saeed
Nov 19, 2023

FAQs

What is urea?

A waste product from protein breakdown, excreted in urine.
Huma Saeed
Dec 06, 2023

Where is urea excreted?

Primarily through the kidneys in urine.
Huma Saeed
Dec 06, 2023

How is uric acid formed?

From the breakdown of purines in the body.
Harlon Moss
Dec 06, 2023

How is urea formed?

In the liver from the breakdown of amino acids.
Huma Saeed
Dec 06, 2023

What conditions are associated with high uric acid?

Gout, kidney stones, and renal failure.
Huma Saeed
Dec 06, 2023

How is uric acid excreted?

Through the kidneys, but can accumulate in the body.
Aimie Carlson
Dec 06, 2023

What are the health risks of high urea levels?

Indicate potential kidney problems.
Aimie Carlson
Dec 06, 2023

What is uric acid?

A byproduct of purine metabolism, potentially causing gout.
Sumera Saeed
Dec 06, 2023

Can urea be toxic?

High levels can be toxic and indicate kidney issues.
Janet White
Dec 06, 2023

Is uric acid always harmful?

Not always, but high levels can cause health issues.
Huma Saeed
Dec 06, 2023

What are normal uric acid levels?

Typically 3.4-7.0 mg/dL for men and 2.4-6.0 mg/dL for women.
Huma Saeed
Dec 06, 2023

Does uric acid have any beneficial role?

It acts as an antioxidant.
Huma Saeed
Dec 06, 2023

How can uric acid levels be managed?

With medication and diet low in purines.
Harlon Moss
Dec 06, 2023

What foods increase uric acid?

Red meat, seafood, and alcohol.
Harlon Moss
Dec 06, 2023

Can lifestyle changes reduce uric acid?

Yes, diet and hydration play a significant role.
Janet White
Dec 06, 2023

What are normal urea levels?

Generally, 7-20 mg/dL in blood tests.
Aimie Carlson
Dec 06, 2023

Is urea used in agriculture?

Yes, as a nitrogen-rich fertilizer.
Janet White
Dec 06, 2023

How can urea levels be reduced?

Through proper kidney function and hydration.
Aimie Carlson
Dec 06, 2023

Is urea present in cosmetics?

Yes, for its moisturizing properties.
Harlon Moss
Dec 06, 2023

Do urea levels affect hydration?

They can indicate hydration levels and kidney function.
Aimie Carlson
Dec 06, 2023
About Author
Written by
Huma Saeed
Huma is a renowned researcher acclaimed for her innovative work in Difference Wiki. Her dedication has led to key breakthroughs, establishing her prominence in academia. Her contributions continually inspire and guide her field.
Edited by
Sumera Saeed
Sumera is an experienced content writer and editor with a niche in comparative analysis. At Diffeence Wiki, she crafts clear and unbiased comparisons to guide readers in making informed decisions. With a dedication to thorough research and quality, Sumera's work stands out in the digital realm. Off the clock, she enjoys reading and exploring diverse cultures.

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