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Ferrous Sulfate vs. Iron Glycinate: What's the Difference?

Edited by Huma Saeed || By Sumera Saeed || Published on January 11, 2024
Ferrous sulfate is a common iron supplement used to treat anemia; iron glycinate is a gentler, highly bioavailable form of iron supplement.

Key Differences

Ferrous sulfate is an iron salt, a combination of iron and sulfuric acid. Iron glycinate, also known as ferrous bisglycinate, is iron chelated with glycine, making it more absorbable.
Sumera Saeed
Jan 11, 2024
Ferrous sulfate is effective but can be harsh on the stomach and may cause gastrointestinal side effects. Iron glycinate offers higher bioavailability and is gentler on the digestive system, reducing the likelihood of side effects.
Sumera Saeed
Jan 11, 2024
Both are used to treat iron deficiency and anemia. Ferrous sulfate is often the first choice due to its effectiveness and lower cost. Iron glycinate is preferred when patients experience side effects from other iron supplements.
Huma Saeed
Jan 11, 2024
Ferrous sulfate may require higher doses to achieve desired iron levels but can lead to constipation or stomach upset. Iron glycinate can be taken in lower doses due to its higher absorption rate, minimizing gastrointestinal issues.
Sumera Saeed
Jan 11, 2024
Ferrous sulfate is widely prescribed but may not be suitable for everyone due to its side effects. Iron glycinate is often recommended for those who have difficulty tolerating other iron supplements, including pregnant women and individuals with sensitive stomachs.
Janet White
Jan 11, 2024
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Comparison Chart

Chemical Form

Iron salt (iron and sulfuric acid)
Iron chelated with glycine
Huma Saeed
Jan 11, 2024

Bioavailability and Absorption

Lower bioavailability, harsher on stomach
Higher bioavailability, gentler on the digestive system
Sumera Saeed
Jan 11, 2024

Common Use

First-line treatment for anemia
Used when patients have side effects from other iron forms
Sumera Saeed
Jan 11, 2024

Side Effects

May cause gastrointestinal issues
Fewer gastrointestinal side effects
Aimie Carlson
Jan 11, 2024

Dosage and Administration

Often requires higher doses
Effective at lower doses
Aimie Carlson
Jan 11, 2024
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Ferrous Sulfate and Iron Glycinate Definitions

Ferrous Sulfate

Gastrointestinal Effects.
Some people experience stomach upset from ferrous sulfate.
Aimie Carlson
Dec 11, 2023

Iron Glycinate

Highly Absorbable Iron.
Iron glycinate is preferred for its high bioavailability.
Huma Saeed
Dec 11, 2023

Ferrous Sulfate

Anemia Treatment.
Doctors often prescribe ferrous sulfate for iron-deficiency anemia.
Sumera Saeed
Dec 11, 2023

Iron Glycinate

Chelated Iron Form.
Iron glycinate is iron chelated with glycine for better absorption.
Sumera Saeed
Dec 11, 2023

Ferrous Sulfate

Common Iron Form.
Ferrous sulfate is a widely used iron supplement.
Harlon Moss
Dec 11, 2023

Iron Glycinate

Gentle Iron Supplement.
Iron glycinate is recommended for its gentle effect on the stomach.
Sumera Saeed
Dec 11, 2023

Ferrous Sulfate

Iron Supplement.
Ferrous sulfate supplements are used to treat anemia.
Sumera Saeed
Dec 11, 2023

Iron Glycinate

Suitable for Sensitive Stomachs.
For those with stomach issues, iron glycinate is often advised.
Sumera Saeed
Dec 11, 2023

Ferrous Sulfate

Iron Salt Form.
Ferrous sulfate is a form of iron combined with sulfuric acid.
Sumera Saeed
Dec 11, 2023

Iron Glycinate

Effective at Lower Doses.
Iron glycinate can be taken in lower doses due to its efficiency.
Aimie Carlson
Dec 11, 2023

FAQs

Why is ferrous sulfate commonly prescribed?

For its effectiveness in treating iron deficiency anemia.
Sumera Saeed
Jan 11, 2024

Can ferrous sulfate cause side effects?

Yes, it can cause gastrointestinal issues like constipation or stomach upset.
Sumera Saeed
Jan 11, 2024

What is ferrous sulfate?

A common iron supplement used to treat iron deficiency.
Sumera Saeed
Jan 11, 2024

Why might someone prefer iron glycinate?

Due to its higher bioavailability and fewer gastrointestinal side effects.
Janet White
Jan 11, 2024

Is iron glycinate more expensive than ferrous sulfate?

Generally, iron glycinate is more expensive.
Harlon Moss
Jan 11, 2024

What makes iron glycinate different in terms of absorption?

It's chelated, making it easier for the body to absorb without causing discomfort.
Aimie Carlson
Jan 11, 2024

Can ferrous sulfate interact with other medications?

Yes, it can interact with certain medications and should be taken under guidance.
Janet White
Jan 11, 2024

What is iron glycinate?

A form of iron supplement that is gentler on the stomach.
Huma Saeed
Jan 11, 2024

Is iron glycinate safe for pregnant women?

Yes, it's often recommended due to its gentler nature.
Sumera Saeed
Jan 11, 2024

Can children take ferrous sulfate?

Yes, but under medical supervision and appropriate dosing.
Sumera Saeed
Jan 11, 2024

How does the body absorb ferrous sulfate?

It's absorbed in the gut but can be harsh on the stomach.
Janet White
Jan 11, 2024

Does ferrous sulfate affect stool color?

It can darken the stool, which is normal when taking iron supplements.
Aimie Carlson
Jan 11, 2024

Can either supplement cause allergic reactions?

While rare, allergic reactions can occur with any supplement.
Harlon Moss
Jan 11, 2024

Is iron glycinate suitable for vegans?

Yes, it's also free from animal-derived ingredients.
Janet White
Jan 11, 2024

Is ferrous sulfate vegan?

Yes, it does not contain animal-derived ingredients.
Sumera Saeed
Jan 11, 2024

How is iron glycinate taken?

Usually in capsule or tablet form, as directed by a healthcare provider.
Aimie Carlson
Jan 11, 2024

Can either supplement cure anemia permanently?

They treat anemia caused by iron deficiency but may not cure underlying causes.
Aimie Carlson
Jan 11, 2024

Is iron glycinate a good option for long-term use?

Yes, especially for individuals who need ongoing iron supplementation.
Harlon Moss
Jan 11, 2024

How quickly do ferrous sulfate supplements work?

Improvement in symptoms can be seen in a few weeks.
Aimie Carlson
Jan 11, 2024

Does iron glycinate have any impact on stool?

Less likely than ferrous sulfate, due to its gentler nature.
Harlon Moss
Jan 11, 2024
About Author
Written by
Sumera Saeed
Sumera is an experienced content writer and editor with a niche in comparative analysis. At Diffeence Wiki, she crafts clear and unbiased comparisons to guide readers in making informed decisions. With a dedication to thorough research and quality, Sumera's work stands out in the digital realm. Off the clock, she enjoys reading and exploring diverse cultures.
Edited by
Huma Saeed
Huma is a renowned researcher acclaimed for her innovative work in Difference Wiki. Her dedication has led to key breakthroughs, establishing her prominence in academia. Her contributions continually inspire and guide her field.

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