Difference Wiki

Centrifusion vs. Centrifugation: What's the Difference?

Edited by Aimie Carlson || By Harlon Moss || Updated on November 3, 2023
Centrifusion is a term popularized by Nespresso for a coffee brewing process, while centrifugation is a laboratory technique for separating substances.

Key Differences

Centrifusion is a trademarked term created by Nespresso, combining "centrifuge" with "infusion" to describe their coffee brewing method that spins the capsule at high speed to blend the ground coffee with water. Centrifugation, in contrast, is a scientific process used to separate components of a mixture by spinning it at high speed, which forces heavier materials to the outer edge.
Centrifusion is specifically designed for optimal extraction of coffee flavors and aromas in Nespresso machines. It involves a unique blend of centrifugal force and water infusion, whereas centrifugation is a broad term used across many scientific fields including biology and chemistry, and does not involve infusion.
The principle behind centrifusion relates to achieving a particular quality of coffee brew, with equipment designed for consumer use. Centrifugation, however, is a critical process in laboratory settings, where it is used to purify cells, viruses, proteins, and nucleic acids.
In the context of coffee brewing, centrifusion is a proprietary process with a specific application, and you would not use the term in any other context. Centrifugation, on the other hand, is a generic term for a widely applied technique in many scientific procedures.
Centrifusion relies on a machine that can control the interaction between water and coffee grounds, specifically designed by a single company. Centrifugation is used in various types of equipment like benchtop centrifuges, ultracentrifuges, and microcentrifuges, which are made by many manufacturers and have diverse applications.

Comparison Chart


A brewing method that spins coffee capsules.
A technique to separate mixtures by spinning.


Exclusive to Nespresso coffee machines.
Used in laboratories for biological and chemical analyses.


To blend coffee with water for flavor extraction.
To separate components based on density.


Consumer coffee brewing.
Scientific research, medical diagnostics, and more.

Associated Equipment

Nespresso machines.
Laboratory centrifuges.

Centrifusion and Centrifugation Definitions


A method combining centrifugal action and water infusion.
Centrifusion ensures even mixing of water and coffee grounds.


The process of separating substances via rapid spinning.
Centrifugation helped us isolate the blood cells from plasma.


Nespresso's process of spinning coffee capsules for brewing.
The centrifusion technology in my coffee machine makes a rich espresso.


A laboratory technique for sample separation.
We used centrifugation to purify the bacterial culture.


Nespresso's patented coffee extraction process.
The machine's centrifusion feature is easy to use and clean.


Spinning a mixture to separate out its components.
The sediment was collected after centrifugation of the suspension.


High-speed spinning involved in Nespresso coffee machines.
Thanks to centrifusion, the coffee has a smooth and frothy crema.


The action of using a centrifuge to separate mixtures.
She set the centrifuge to 10,000 rpm for the centrifugation of her samples.


A unique brewing technique by Nespresso.
The centrifusion system is what sets Nespresso machines apart.


A method to separate particles based on density.
Centrifugation is critical in preparing samples for electron microscopy.


Centrifugal infusion


An apparatus consisting essentially of a compartment spun about a central axis to separate contained materials of different specific gravities, or to separate colloidal particles suspended in a liquid.


An apparatus in which humans or animals are enclosed and which is revolved to simulate the effects of acceleration in a spacecraft.


What is centrifugation?

Centrifugation is a method to separate mixture components by spinning at high speeds.

What is centrifusion?

Centrifusion is Nespresso's coffee brewing process involving spinning capsules.

Are centrifusion and centrifugation interchangeable terms?

No, they refer to different processes in different contexts.

Is centrifusion used in coffee shops?

It's primarily for home use in Nespresso machines.

Can centrifusion be used in a laboratory setting?

No, it is specific to Nespresso coffee machines.

Is centrifusion related to espresso making?

Yes, specifically for Nespresso's version of espresso.

Is centrifusion patented?

Yes, it is a patented technology by Nespresso.

What types of mixtures can be separated by centrifugation?

Biological samples, chemicals, and other laboratory mixtures.

What equipment is necessary for centrifugation?

A laboratory centrifuge is essential for centrifugation.

What scientific fields use centrifugation?

Biology, chemistry, and medicine, among others.

Can I buy a centrifusion machine?

Yes, Nespresso machines with centrifusion are commercially available.

What is the key benefit of centrifusion?

It provides a consistent and high-quality coffee brew.

Do centrifusion and centrifugation require water?

Centrifusion uses water for coffee brewing; centrifugation does not necessarily require water.

Are there different types of centrifugation?

Yes, including differential, density gradient, and isopycnic centrifugation.

What precautions are necessary for centrifugation?

Proper balancing, correct RPM settings, and use of safety lids are crucial.

Can centrifugation be done at home?

It's not common, as it requires a centrifuge, which is usually found in labs.

Is centrifugation used in DNA extraction?

Yes, it's a standard step in DNA extraction protocols.

How does centrifusion affect coffee taste?

It's designed to enhance flavor extraction and crema.

Does centrifusion require special capsules?

Yes, it requires Nespresso capsules designed for the process.

What are the speeds involved in centrifugation?

They can range from a few hundred to hundreds of thousands of RPM.
About Author
Written by
Harlon Moss
Harlon is a seasoned quality moderator and accomplished content writer for Difference Wiki. An alumnus of the prestigious University of California, he earned his degree in Computer Science. Leveraging his academic background, Harlon brings a meticulous and informed perspective to his work, ensuring content accuracy and excellence.
Edited by
Aimie Carlson
Aimie Carlson, holding a master's degree in English literature, is a fervent English language enthusiast. She lends her writing talents to Difference Wiki, a prominent website that specializes in comparisons, offering readers insightful analyses that both captivate and inform.

Trending Comparisons

Popular Comparisons

New Comparisons