Difference Wiki

Amlodipine vs. Amlodipine Besylate: What's the Difference?

Edited by Huma Saeed || By Sumera Saeed || Published on December 18, 2023
Amlodipine is a calcium channel blocker used to treat hypertension, while amlodipine besylate is the besylate salt form of amlodipine, more stable and easier to formulate in medications.

Key Differences

Amlodipine is a drug in the dihydropyridine class of calcium channel blockers. While, amlodipine besylate is the same drug in a salt form, combined with benzenesulfonate (besylate) for stability.
Sumera Saeed
Dec 18, 2023
The pure form of amlodipine is rarely used in medications due to stability issues. Amlodipine besylate, on the other hand, is commonly used in pharmaceuticals due to its improved stability and solubility.
Sumera Saeed
Dec 18, 2023
Both are used to treat high blood pressure and angina, but the besylate form is more commonly prescribed due to its formulation. The effectiveness of both in treating cardiovascular conditions is the same.
Huma Saeed
Dec 18, 2023
In the body, amlodipine besylate converts to amlodipine, meaning their bioavailability and absorption rates are essentially the same.
Aimie Carlson
Dec 18, 2023
The pharmacokinetics, including how the body metabolizes and eliminates the drug, are the same for both forms. The besylate component does not significantly alter the drug’s action.
Harlon Moss
Dec 18, 2023
ADVERTISEMENT

Comparison Chart

Chemical Form

Pure drug form
Salt form with besylate
Sumera Saeed
Dec 18, 2023

Stability in Formulation

Less stable, rarely used in pure form
More stable, commonly used in medications
Sumera Saeed
Dec 18, 2023

Usage

Treats hypertension and angina
Same uses, more prevalent in prescriptions
Sumera Saeed
Dec 18, 2023

Bioavailability

Effective absorption
Converts to amlodipine in the body, similar effect
Harlon Moss
Dec 18, 2023

Pharmacokinetics

Same metabolic process
Same, with the besylate component being inert
Janet White
Dec 18, 2023
ADVERTISEMENT

Amlodipine and Amlodipine Besylate Definitions

Amlodipine

A calcium channel blocker medication.
Amlodipine is prescribed for high blood pressure control.
Sumera Saeed
Dec 01, 2023

Amlodipine Besylate

Has the same therapeutic effects as amlodipine.
Amlodipine besylate effectively treats angina, just like amlodipine.
Sumera Saeed
Dec 01, 2023

Amlodipine

Used in the treatment of angina and coronary artery disease.
Doctors often recommend amlodipine for chest pain relief.
Sumera Saeed
Dec 01, 2023

Amlodipine Besylate

Facilitates easier manufacturing and storage of the drug.
Pharmaceutical companies prefer amlodipine besylate for production.
Harlon Moss
Dec 01, 2023

Amlodipine

Works by relaxing blood vessels and improving blood flow.
Amlodipine helps in reducing the risk of stroke and heart attack.
Janet White
Dec 01, 2023

Amlodipine Besylate

Offers improved stability over pure amlodipine.
Due to its stability, amlodipine besylate has a longer shelf life.
Sumera Saeed
Dec 01, 2023

Amlodipine

Belongs to the dihydropyridine class of drugs.
As a dihydropyridine, amlodipine has fewer cardiac side effects.
Harlon Moss
Dec 01, 2023

Amlodipine Besylate

Converts to amlodipine in the body after ingestion.
Once ingested, amlodipine besylate effectively lowers blood pressure.
Sumera Saeed
Dec 01, 2023

Amlodipine

Can be used alone or with other medications.
Amlodipine is sometimes combined with other antihypertensives.
Harlon Moss
Dec 01, 2023

Amlodipine Besylate

The besylate salt form of amlodipine.
Amlodipine besylate is more commonly used in pill formulations.
Huma Saeed
Dec 01, 2023

Amlodipine

(pharmaceutical drug) A long-acting calcium channel blocker used as an anti-hypertensive and in the treatment of angina
Sumera Saeed
Nov 30, 2023

FAQs

What is amlodipine besylate?

The besylate salt form of amlodipine, used for the same purposes.
Huma Saeed
Dec 18, 2023

Can amlodipine treat heart failure?

It's not the primary treatment but can be used to manage symptoms.
Harlon Moss
Dec 18, 2023

What is amlodipine?

A calcium channel blocker used to treat hypertension and angina.
Sumera Saeed
Dec 18, 2023

Does amlodipine have side effects?

Possible side effects include dizziness, swelling, or fatigue.
Sumera Saeed
Dec 18, 2023

Are the effects of amlodipine and its besylate form different?

No, they have the same therapeutic effect.
Janet White
Dec 18, 2023

Is amlodipine effective for high blood pressure?

Very effective in lowering and managing blood pressure.
Aimie Carlson
Dec 18, 2023

Why is amlodipine besylate more common?

It’s more stable and easier to manufacture.
Sumera Saeed
Dec 18, 2023

Can amlodipine besylate cause drowsiness?

Drowsiness is a possible side effect.
Sumera Saeed
Dec 18, 2023

Does amlodipine besylate interact with other drugs?

Yes, it can interact with certain drugs, so consultation is important.
Sumera Saeed
Dec 18, 2023

Can amlodipine cause weight gain?

Weight gain is a rare but possible side effect.
Sumera Saeed
Dec 18, 2023

Is amlodipine besylate available over the counter?

No, it requires a doctor's prescription.
Harlon Moss
Dec 18, 2023

Does amlodipine affect kidney function?

It can be used safely in patients with kidney disease, with monitoring.
Aimie Carlson
Dec 18, 2023

Can amlodipine besylate be stopped abruptly?

Stopping suddenly is not recommended; tapering is safer.
Aimie Carlson
Dec 18, 2023

Is amlodipine besylate safe for long-term use?

Yes, under medical supervision.
Harlon Moss
Dec 18, 2023

How should amlodipine be taken?

Usually taken once daily, with or without food.
Janet White
Dec 18, 2023

Can amlodipine besylate be used in pregnancy?

Its use in pregnancy should be discussed with a doctor.
Harlon Moss
Dec 18, 2023

How is amlodipine besylate metabolized?

It’s metabolized in the liver and excreted in urine.
Aimie Carlson
Dec 18, 2023

Is amlodipine suitable for elderly patients?

Yes, but with careful dose adjustments and monitoring.
Janet White
Dec 18, 2023

How long does amlodipine take to work?

It starts working within a few hours, but full effect may take weeks.
Harlon Moss
Dec 18, 2023

Can amlodipine besylate cause coughing?

Coughing is a less common side effect compared to other blood pressure medications.
Sumera Saeed
Dec 18, 2023
About Author
Written by
Sumera Saeed
Sumera is an experienced content writer and editor with a niche in comparative analysis. At Diffeence Wiki, she crafts clear and unbiased comparisons to guide readers in making informed decisions. With a dedication to thorough research and quality, Sumera's work stands out in the digital realm. Off the clock, she enjoys reading and exploring diverse cultures.
Edited by
Huma Saeed
Huma is a renowned researcher acclaimed for her innovative work in Difference Wiki. Her dedication has led to key breakthroughs, establishing her prominence in academia. Her contributions continually inspire and guide her field.

Trending Comparisons

Popular Comparisons

New Comparisons