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ADH vs. Aldosterone: What's the Difference?

Edited by Sumera Saeed || By Sawaira Riaz || Published on October 12, 2023
ADH (antidiuretic hormone) regulates water reabsorption in kidneys; Aldosterone controls sodium and potassium balance.

Key Differences

ADH, also known as vasopressin, and Aldosterone are both hormones that play crucial roles in the body's fluid and electrolyte balance. However, their primary functions and modes of action differ significantly.
Sawaira Riaz
Oct 12, 2023
ADH primarily influences the amount of water reabsorbed by the kidneys, helping regulate the body's overall water balance. When ADH levels rise, more water is reabsorbed, concentrating the urine and maintaining hydration.
Sawaira Riaz
Oct 12, 2023
Aldosterone, on the other hand, chiefly affects the reabsorption of sodium and the excretion of potassium in the kidneys. This not only regulates electrolyte balance but also indirectly affects water retention, since where sodium goes, water often follows.
Sawaira Riaz
Oct 12, 2023
ADH's secretion is primarily triggered by increased blood osmolarity or low blood volume, signaling the body to conserve water. In contrast, Aldosterone is mainly secreted in response to low blood sodium or high blood potassium levels.
Janet White
Oct 12, 2023
In essence, while both ADH and Aldosterone are pivotal for maintaining the body's fluid and electrolyte homeostasis, ADH focuses on water conservation, whereas Aldosterone emphasizes sodium-potassium balance.
Sara Rehman
Oct 12, 2023
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Comparison Chart

Primary Function

Regulates water reabsorption
Controls sodium-potassium balance
Sawaira Riaz
Oct 12, 2023

Origin

Posterior pituitary
Adrenal cortex
Sawaira Riaz
Oct 12, 2023

Trigger for Release

Increased blood osmolarity, low blood volume
Low blood sodium, high blood potassium
Sawaira Riaz
Oct 12, 2023

Effect on Kidneys

Increases water reabsorption
Increases sodium reabsorption, potassium excretion
Sawaira Riaz
Oct 12, 2023

Overall Role

Maintains body's water balance
Maintains electrolyte and volume homeostasis
Sawaira Riaz
Oct 12, 2023
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ADH and Aldosterone Definitions

ADH

ADH acts on the kidneys' collecting ducts.
In response to ADH, kidneys reabsorb more water back into the bloodstream.
Sawaira Riaz
Oct 09, 2023

Aldosterone

Aldosterone plays a role in maintaining blood volume and pressure.
By influencing sodium retention, Aldosterone can indirectly affect blood volume and pressure.
Sara Rehman
Oct 09, 2023

ADH

ADH is a hormone that promotes water retention in the body.
High levels of ADH lead to decreased urine production.
Sawaira Riaz
Oct 09, 2023

Aldosterone

Aldosterone affects sodium and potassium levels in urine.
High Aldosterone levels promote sodium reabsorption and potassium excretion.
Aimie Carlson
Oct 09, 2023

ADH

ADH is released by the posterior pituitary gland.
The synthesis and release of ADH occur in the brain.
Sawaira Riaz
Oct 09, 2023
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Aldosterone

Aldosterone is produced in the adrenal cortex.
The adrenal glands, located above the kidneys, produce Aldosterone.
Janet White
Oct 09, 2023

ADH

ADH plays a role in osmoregulation.
ADH secretion increases when blood becomes too concentrated.
Sawaira Riaz
Oct 09, 2023

Aldosterone

Aldosterone's release is influenced by the renin-angiotensin system.
Low blood pressure can trigger the renin-angiotensin system, leading to Aldosterone secretion.
Sawaira Riaz
Oct 09, 2023

ADH

ADH's levels can influence blood pressure.
Elevated ADH can lead to increased blood pressure due to water retention.
Harlon Moss
Oct 09, 2023

Aldosterone

Aldosterone is a steroid hormone that regulates electrolytes.
Aldosterone helps maintain sodium and potassium balance in the body.
Sara Rehman
Oct 09, 2023

ADH

Hormone secreted by the posterior pituitary gland (trade name Pitressin) and also by nerve endings in the hypothalamus; affects blood pressure by stimulating capillary muscles and reduces urine flow by affecting reabsorption of water by kidney tubules
Sawaira Riaz
Oct 07, 2023

Aldosterone

A steroid hormone that is produced by the adrenal cortex and regulates salt balance, blood volume, and blood pressure in the body.
Sawaira Riaz
Oct 07, 2023

Aldosterone

(steroid hormone) A mineralocorticoid hormone, secreted by the adrenal cortex, that regulates the balance of sodium and potassium in the body.
Sawaira Riaz
Oct 07, 2023

Aldosterone

A corticosteroid hormone that is secreted by the cortex of the adrenal gland; regulates salt (sodium and potassium) and water balance
Sawaira Riaz
Oct 07, 2023

FAQs

Where is Aldosterone produced?

Aldosterone is produced in the adrenal cortex.
Sawaira Riaz
Oct 12, 2023

Is Aldosterone a steroid hormone?

Yes, Aldosterone is a type of steroid hormone.
Sara Rehman
Oct 12, 2023

What triggers the secretion of Aldosterone?

Low blood sodium or high blood potassium levels mainly trigger Aldosterone secretion.
Sara Rehman
Oct 12, 2023

Which gland secretes ADH?

The posterior pituitary gland secretes ADH.
Aimie Carlson
Oct 12, 2023

How does Aldosterone influence blood volume?

Aldosterone promotes sodium reabsorption, which indirectly affects blood volume due to water following sodium.
Harlon Moss
Oct 12, 2023

Can dehydration affect ADH levels?

Yes, dehydration can lead to increased ADH secretion to conserve water.
Aimie Carlson
Oct 12, 2023

What does ADH primarily regulate?

ADH primarily regulates water reabsorption in the kidneys.
Sawaira Riaz
Oct 12, 2023

Can ADH affect blood pressure?

Yes, elevated ADH can lead to increased blood pressure due to water retention.
Sawaira Riaz
Oct 12, 2023

Do both ADH and Aldosterone act on the kidneys?

Yes, both hormones act on the kidneys but influence different aspects of renal function.
Sara Rehman
Oct 12, 2023

How are ADH and Aldosterone related to the body's homeostasis?

Both hormones play crucial roles in maintaining fluid and electrolyte balance in the body.
Harlon Moss
Oct 12, 2023
About Author
Written by
Sawaira Riaz
Sawaira is a dedicated content editor at difference.wiki, where she meticulously refines articles to ensure clarity and accuracy. With a keen eye for detail, she upholds the site's commitment to delivering insightful and precise content.
Edited by
Sumera Saeed
Sumera is an experienced content writer and editor with a niche in comparative analysis. At Diffeence Wiki, she crafts clear and unbiased comparisons to guide readers in making informed decisions. With a dedication to thorough research and quality, Sumera's work stands out in the digital realm. Off the clock, she enjoys reading and exploring diverse cultures.

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